Calprotectin Monoclonal Antibody (MAC387) | Invitrogen MA1-33972 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Calprotectin Monoclonal Antibody (MAC387)

catalog :

MA1-33972

quantity :

100 ug

price :

US 546.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MAC387

reactivity :

domestic goat, guinea pig, human, mouse, rat, dogs, bovine, pigs , cat, domestic rabbit, domestic horse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; pigs ; 1:400	Elgharably H, Ganesh K, Dickerson J, Khanna S, Abas M, Ghatak P, et al. A modified collagen gel dressing promotes angiogenesis in a preclinical swine model of chronic ischemic wounds. Wound Repair Regen. 2014;22:720-9 pubmed publisher
immunohistochemistry; pigs ; 1:100	Nedorost L, Uemura H, Furck A, Saeed I, Slavik Z, Kobr J, et al. Vascular histopathologic reaction to pulmonary artery banding in an in vivo growing porcine model. Pediatr Cardiol. 2013;34:1652-60 pubmed publisher
flow cytometry; rat	Gauglitz G, Toliver Kinsky T, Williams F, Song J, Cui W, Herndon D, et al. Insulin increases resistance to burn wound infection-associated sepsis. Crit Care Med. 2010;38:202-8 pubmed publisher
	Du Cheyne C, Martens A, De Spiegelaere W. High Numbers of CD163-Positive Macrophages in the Fibrotic Region of Exuberant Granulation Tissue in Horses. Animals (Basel). 2021;11: pubmed publisher
	Linard C, Brachet M, Strup Perrot C, l Homme B, Busson E, Squiban C, et al. Autologous Bone Marrow Mesenchymal Stem Cells Improve the Quality and Stability of Vascularized Flap Surgery of Irradiated Skin in Pigs. Stem Cells Transl Med. 2018;7:569-582 pubmed publisher
	Wonderlich E, Swan Z, Bissel S, Hartman A, Carney J, O Malley K, et al. Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques. J Immunol. 2017;198:1616-1626 pubmed publisher
	Ambe P, Orth V, Gödde D, Zirngibl H. Improving the Preoperative Diagnostic Accuracy of Acute Appendicitis. Can Fecal Calprotectin Be Helpful?. PLoS ONE. 2016;11:e0168769 pubmed publisher
	Ambe P, Gödde D, Bönicke L, Papadakis M, Störkel S, Zirngibl H. Calprotectin could be a potential biomarker for acute appendicitis. J Transl Med. 2016;14:107 pubmed publisher
	Phuah J, Wong E, Gideon H, Maiello P, Coleman M, Hendricks M, et al. Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques. Infect Immun. 2016;84:1301-1311 pubmed publisher
	Gestrich C, Duerr G, Heinemann J, Meertz A, Probst C, Roell W, et al. Activation of Endocannabinoid System Is Associated with Persistent Inflammation in Human Aortic Aneurysm. Biomed Res Int. 2015;2015:456582 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Calprotectin Monoclonal Antibody (MAC387)

Catalog # :

MA1-33972

Quantity :

100 ug

Price :

US 546.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Baboon, Bovine, Canine, Equine, Feline, Goat, Guinea Pig, Human, Mouse, Non-human primate, Rabbit, Rat

Applications :

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:250, Immunohistochemistry (Frozen): 1:100-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:1,000

Species :

Baboon, Bovine, Canine, Equine, Feline, Goat, Guinea Pig, Human, Mouse, Non-human primate, Rabbit, Rat

Clone :

MAC387

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The S100A8/A9 heterocomplex, also called MRP-8/MRP-14 complex or calprotectin, comprises 60% of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes, macrophages and ileal tissue eosinophils. Peripheral blood monocytes carry the antigen extra- and intracellularly, neutrophils only intracellularly. The S100A8/A9 complex has antibacterial, antifungal, immunomodulating and antiproliferative effects. Besides this it is a potent chemotactic factor for neutrophils. Plasma concentrations are elevated in diseases associated with increased neutrophil activity, like inflammatory bowel disease. Granulocytes terminate their existence after transmigration through the intestinal wall. Therefore calprotectin is also detectable in feces. Elevated levels of calprotectin have been observed in body fluids such as plasma, saliva, gingival crevicular fluid, stools, and synovial fluid during infection and inflammatory conditions.

Immunogen :

Human monocytes

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:250, Immunohistochemistry (Frozen): 1:100-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:1,000

Aliases :

60B8Ag; AI323541; AW546964; B8Ag; BEE11; BEE22; CAGA; CAGB; calcium binding protein; S100 protein; calgranulin A; calgranulin B; calgranulin-A; Calgranulin-B; calprotectin; calprotectin L1H subunit; Calprotectin L1L subunit; CFAG; CGLA; CGLB; chemotactic cytokine CP-10; chemotactic S100 protein; CP-10; Cystic fibrosis antigen; EGK_01322; EGK_21438; GAGB; intracellular calcium-binding protein (MRP14); L1AG; Leukocyte L1 complex heavy chain; leukocyte L1 complex light chain; LIAG; LOC100735514; LOC532569 protein; MA387; MAC387; macrophage migration inhibitory factor-related protein-14; macrophage migration inhibitory factor-related protein-8; MIF; migration inhibitory factor-related protein 14; Migration inhibitory factor-related protein 8; Mrp14; MRP-14; MRP8; MRP-8; myeloid-related protein 14; Neutrophil cytosolic 23 kDa protein; neutrophil cytosolic 7 kDa protein; NIF; p14; p23; P7; p8; Pro-inflammatory S100 cytokine; protein S100-A8; Protein S100-A9; S100 calcium binding protein A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium binding protein A9; S100 calcium binding protein A9 (calgranulin B); S100 calcium binding protein A9; protein S100-A9; S100 calcium-binding protein A8; S100 calcium-binding protein A8 (calgranulin A); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B); S100a8; S100A8/S100A9; S100a9; similar to Calgranulin A (Migration inhibitory factor-related protein 8) (MRP-8) (Cystic fibrosis antigen) (CFAG) (P8) (Leukocyte L1 complex light chain) (S100 calcium-binding protein A8) (Calprotectin L1L subunit) (Urinary stone protein band A). ; urinary stone protein band A

more info or order :

Invitrogen product webpage