ICAM-1 Monoclonal Antibody (15.2) | Invitrogen MA1-33754 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ICAM-1 Monoclonal Antibody (15.2)

catalog :

MA1-33754

quantity :

100 µg

price :

US 438

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

15.2

reactivity :

human, mouse, pigs , domestic rabbit

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; pigs	Kim H, Kee P, Rim Y, Moody M, Klegerman M, Vela D, et al. Nitric oxide improves molecular imaging of inflammatory atheroma using targeted echogenic immunoliposomes. Atherosclerosis. 2013;231:252-60 pubmed publisher
immunohistochemistry; human; 20 ug/ml	Hromatka B, Ngeleza S, Adibi J, Niles R, Tshefu A, Fisher S. Histopathologies, immunolocalization, and a glycan binding screen provide insights into Plasmodium falciparum interactions with the human placenta. Biol Reprod. 2013;88:154 pubmed publisher
immunohistochemistry; human	Abreu Velez A, Howard M, Hashimoto T. Palm tissue displaying a polyclonal autoimmune response in patients affected by a new variant of endemic pemphigus foliaceus in Colombia, South America. Eur J Dermatol. 2010;20:74-81 pubmed publisher
immunohistochemistry; human; 1:5000	Kurt M, Zulfikaroglu E, Ucankus N, Omeroglu S, Ozcan U. Expression of intercellular adhesion molecule-1 in umbilical and placental vascular tissue of gestational diabetic and normal pregnancies. Arch Gynecol Obstet. 2010;281:71-6 pubmed publisher
immunocytochemistry; human	Huegel R, Velasco P, De La Luz Sierra M, Christophers E, Schröder J, Schwarz T, et al. Novel anti-inflammatory properties of the angiogenesis inhibitor vasostatin. J Invest Dermatol. 2007;127:65-74 pubmed
	Chevrier S, Levine J, Zanotelli V, Silina K, Schulz D, Bacac M, et al. An Immune Atlas of Clear Cell Renal Cell Carcinoma. Cell. 2017;169:736-749.e18 pubmed publisher
	Sackstein R, Schatton T, Barthel S. T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy. Lab Invest. 2017;97:669-697 pubmed publisher
	Klegerman M, Zou Y, Golunski E, Peng T, Huang S, McPherson D. Use of thermodynamic coupling between antibody-antigen binding and phospholipid acyl chain phase transition energetics to predict immunoliposome targeting affinity. J Liposome Res. 2014;24:216-22 pubmed publisher
	Hamilton A, Huang S, Warnick D, Rabbat M, Kane B, Nagaraj A, et al. Intravascular ultrasound molecular imaging of atheroma components in vivo. J Am Coll Cardiol. 2004;43:453-60 pubmed

product information

Product Type :

Antibody

Product Name :

ICAM-1 Monoclonal Antibody (15.2)

Catalog # :

MA1-33754

Quantity :

100 µg

Pricing :

US 438

Clonality :

Monoclonal

Purity :

Antigen affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Rabbit

Applications :

Flow Cytometry: Assay-dependent, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Neutralization: Assay-dependent, Western Blot: Assay-dependent

Species :

Human, Mouse, Rabbit

Clone :

15.2

Isotype :

IgG1

Storage :

4° C

Description :

ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.

Immunogen :

Human monocytes.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Neutralization: Assay-dependent, Western Blot: Assay-dependent

Aliases :

BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells