product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Collagen I Monoclonal Antibody (COL-1)
catalog :
MA1-26771
quantity :
100 uL
price :
US 480.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
COL-1
reactivity :
human, mouse, rat, bovine, pigs , domestic rabbit
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, dot blot
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:250; loading ...
Bersini S, Schulte R, Huang L, Tsai H, Hetzer M. Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome. elife. 2020;9: pubmed publisher
  • ELISA; human; 1:2000; fig 9
Kobielarz M, Szotek S, Głowacki M, Dawidowicz J, Pezowicz C. Qualitative and quantitative assessment of collagen and elastin in annulus fibrosus of the physiologic and scoliotic intervertebral discs. J Mech Behav Biomed Mater. 2016;62:45-56 pubmed publisher
  • western blot; human
Sémiramoth N, Gleizes A, Turbica I, Sandré C, Marin Esteban V, Gorges R, et al. Afa/Dr-expressing, diffusely adhering Escherichia coli strain C1845 triggers F1845 fimbria-dependent phosphatidylserine externalization on neutrophil-like differentiated PLB-985 cells through an apoptosis-independent mechanism. Infect Immun. 2010;78:2974-83 pubmed publisher
  • ELISA; human
Ko Y, Maeng J, Ahn Y, Hwang S, Cho N, Lee S. Microchip-based multiplex electro-immunosensing system for the detection of cancer biomarkers. Electrophoresis. 2008;29:3466-76 pubmed publisher
  • immunohistochemistry; mouse; 1:200
Cusi M, Del Vecchio M, Terrosi C, Savellini G, Di Genova G, La Placa M, et al. Immune-reconstituted influenza virosome containing CD40L gene enhances the immunological and protective activity of a carcinoembryonic antigen anticancer vaccine. J Immunol. 2005;174:7210-6 pubmed
Barbosa F, Garrudo F, Marques A, Cabral J, Morgado J, Ferreira F, et al. Novel Electroactive Mineralized Polyacrylonitrile/PEDOT:PSS Electrospun Nanofibers for Bone Repair Applications. Int J Mol Sci. 2023;24: pubmed publisher
Barbosa F, Garrudo F, Alberte P, Resina L, Carvalho M, Jain A, et al. Hydroxyapatite-filled osteoinductive and piezoelectric nanofibers for bone tissue engineering. Sci Technol Adv Mater. 2023;24:2242242 pubmed publisher
Villase xf1 or Cer xf3 n L, Mendoza Anaya D, L xf3 pez Ortiz S, Rosales Iba xf1 ez R, Rodr xed guez Mart xed nez J, Reyes Valderrama M, et al. Biocompatibility analysis and chemical characterization of Mn-doped hydroxyapatite. J Mater Sci Mater Med. 2023;34:40 pubmed publisher
Kim M, Lee J, Lee S, Chang H, Park J, Park C. The Role of Erythrocyte Membrane Protein Band 4.1-like 3 in Idiopathic Pulmonary Fibrosis. Int J Mol Sci. 2023;24: pubmed publisher
Yamada S, Yassin M, Torelli F, Hansmann J, Green J, Schwarz T, et al. Unique osteogenic profile of bone marrow stem cells stimulated in perfusion bioreactor is Rho-ROCK-mediated contractility dependent. Bioeng Transl Med. 2023;8:e10509 pubmed publisher
Wang H, Poe A, Martinez Yus M, Pak L, Nandakumar K, Santhanam L. Lysyl oxidase-like 2 processing by factor Xa modulates its activity and substrate preference. Commun Biol. 2023;6:375 pubmed publisher
Lee S, Lee M, Jo S, Yoo I, Sarankhuu B, Kim H, et al. Effects and Mechanism of Particulate Matter on Tendon Healing Based on Integrated Analysis of DNA Methylation and RNA Sequencing Data in a Rat Model. Int J Mol Sci. 2022;23: pubmed publisher
Gregory E, Baek I, Ala Kokko N, Dugan R, Pinzon Herrera L, Almod xf3 var J, et al. Peripheral Nerve Decellularization for In Vitro Extracellular Matrix Hydrogel Use: A Comparative Study. ACS Biomater Sci Eng. 2022;8:2574-2588 pubmed publisher
Savin I, Markov A, Zenkova M, Sen kova A. Asthma and Post-Asthmatic Fibrosis: A Search for New Promising Molecular Markers of Transition from Acute Inflammation to Pulmonary Fibrosis. Biomedicines. 2022;10: pubmed publisher
Dahl S, Pfundstein S, Hunkeler R, Dong X, Knopfel T, Spielmann P, et al. Fate-mapping of erythropoietin-producing cells in mouse models of hypoxaemia and renal tissue remodelling reveals repeated recruitment and persistent functionality. Acta Physiol (Oxf). 2022;234:e13768 pubmed publisher
Wang H, Poe A, Pak L, Nandakumar K, Jandu S, Steppan J, et al. An in situ activity assay for lysyl oxidases. Commun Biol. 2021;4:840 pubmed publisher
Nerger B, Jaslove J, Elashal H, Mao S, Kosmrlj A, Link A, et al. Local accumulation of extracellular matrix regulates global morphogenetic patterning in the developing mammary gland. Curr Biol. 2021;31:1903-1917.e6 pubmed publisher
Fu W, Liao Q, Li L, Shi Y, Zeng A, Zeng C, et al. An Aurora Kinase B-Based Mouse System to Efficiently Identify and Analyze Proliferating Cardiomyocytes. Front Cell Dev Biol. 2020;8:570252 pubmed publisher
Bhattacharya S, Calar K, Evans C, Petrasko M, de la Puente P. Bioengineering the Oxygen-Deprived Tumor Microenvironment Within a Three-Dimensional Platform for Studying Tumor-Immune Interactions. Front Bioeng Biotechnol. 2020;8:1040 pubmed publisher
Chen J, Lazarenko O, Zhao H, Wankhade U, Pedersen K, Watt J, et al. Nox4 Expression Is Not Required for OVX-Induced Osteoblast Senescence and Bone Loss in Mice. JBMR Plus. 2020;4:e10376 pubmed publisher
Hensel J, Khattar V, Ashton R, Ponnazhagan S. Recombinant AAV-CEA Tumor Vaccine in Combination with an Immune Adjuvant Breaks Tolerance and Provides Protective Immunity. Mol Ther Oncolytics. 2019;12:41-48 pubmed publisher
Ebrahim N, Mostafa O, El Dosoky R, Ahmed I, Saad A, Mostafa A, et al. Human mesenchymal stem cell-derived extracellular vesicles/estrogen combined therapy safely ameliorates experimentally induced intrauterine adhesions in a female rat model. Stem Cell Res Ther. 2018;9:175 pubmed publisher
Vera Ramirez L, Vodnala S, Nini R, Hunter K, Green J. Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence. Nat Commun. 2018;9:1944 pubmed publisher
Chen C, Wang H, Zhu G, Sun Z, Xu X, Li F, et al. Three-dimensional poly lactic-co-glycolic acid scaffold containing autologous platelet-rich plasma supports keloid fibroblast growth and contributes to keloid formation in a nude mouse model. J Dermatol Sci. 2018;89:67-76 pubmed publisher
Sabry D, Mostafa A, Marzouk S, Ibrahim W, Ali H, Hassan A, et al. Neupogen and mesenchymal stem cells are the novel therapeutic agents in regeneration of induced endometrial fibrosis in experimental rats. Biosci Rep. 2017;37: pubmed publisher
Guo Y, Wu W, Cen Z, Li X, Kong Q, Zhou Q. IL-22-producing Th22 cells play a protective role in CVB3-induced chronic myocarditis and dilated cardiomyopathy by inhibiting myocardial fibrosis. Virol J. 2014;11:230 pubmed publisher
Czuchra A, Meyer H, Legate K, Brakebusch C, Fassler R. Genetic analysis of beta1 integrin "activation motifs" in mice. J Cell Biol. 2006;174:889-99 pubmed
product information
Product Type :
Antibody
Product Name :
Collagen I Monoclonal Antibody (COL-1)
Catalog # :
MA1-26771
Quantity :
100 uL
Price :
US 480.00
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Bovine, Deer, Human, Mouse, Porcine, Rabbit, Rat
Applications :
Dot Blot: Assay-dependent, ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:2,000, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Species :
Bovine, Deer, Human, Mouse, Porcine, Rabbit, Rat
Clone :
COL-1
Isotype :
IgG1
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Collagen I is a Type I collagen with a triple helix structure comprised of two alpha-1 chains and one alpha-2 chain. Collagen I is a member of group I collagen (fibril-forming collagen) found in most connective tissues, and is abundant in bone, cornea, dermis and tendon. Mutations in the COL1A2 gene encoding the alpha-2 chain are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in the COL1A2 gene which codes for the alpha-2 chain, however, tend to be less severe than mutations in the COL1A1 gene, reflecting the different role of alpha-2 chains in matrix integrity. Reciprocal translocations between chromosomes 17 and 22, where Collagen Type 1 genes and the gene for platelet derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified.
Immunogen :
Bovine skin collagen type I
Format :
Liquid
Applications w/Dilutions :
Dot Blot: Assay-dependent, ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:2,000, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Aliases :
AA960264; AI325291; alpha 1 type I collagen; alpha 2 type I collagen; alpha 2 type I procollagen; alpha 2(I) collagen; alpha 2(I) procollagen; alpha 2(I)-collagen; alpha1 chain of type I collagen; alpha-1 collagen (I); alpha-1 type 1 collagen; alpha-1 type I collagen; alpha-1 type-1 collagen; alpha1(I) procollagen; alpha2 chain of type I collagen; alpha-2 type I collagen; alpha-2(1) collagen; alpha2(I) collagen; COL1; Col1a1; Col1a-1; COL1A1; matrix protein; Col1a2; Col1a-2; COLA; Cola1; Cola-1; Cola2; Cola-2; COLIA1; collagen; collagen 1 alpha 2 chain; collagen a2; collagen alpha 1 chain type I; collagen alpha 2(I) chain precursor; collagen alpha-1 chain; collagen alpha-1 chain precursor; collagen alpha-1(I) chain; collagen alpha-1(I) chain preproprotein; collagen alpha-2; collagen alpha-2 chain precursor; collagen alpha-2(I) chain; collagen COL1A2; collagen I alpha-2 polypeptide; collagen I, alpha-2 polypeptide; collagen of skin, tendon and bone, alpha-1 chain; collagen of skin, tendon and bone, alpha-2 chain; collagen type I alpha 1; collagen type I alpha 1 chain; collagen type I alpha 2 chain; collagen, type 1, alpha 1; collagen, type I, alpha 1; collagen, type I, alpha 2; EDSC; Mov13; Mov-13; OI1; OI2; OI3; OI4; oim; osteogenesis imperfecta; precollagen alpha-2; prepro-alpha-1 collagen type I; pro-alpha-1 collagen type 1; procollagen type I, alpha 1; procollagen, type 1, alpha 1; procollagen, type I, alpha 1; procollagen, type I, alpha 2; similar to pro alpha 1(I) collagen; Type I Collagen; type I collagen alpha 1 chain; type I collagen alpha1; type I collagen alpha-2 chain; type I collagen pre-pro-alpha1(I) chain; type I proalpha 1; type I procollagen; type I procollagen alpha 1 chain; type I-alpha 1 collagen
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA