| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 5d
| Moquin D, Genois M, Zhang J, Ouyang J, Yadav T, Buisson R, et al. Localized protein biotinylation at DNA damage sites identifies ZPET, a repressor of homologous recombination. Genes Dev. 2019;33:75-89 pubmed publisher |
- immunocytochemistry; human
| Mortusewicz O, Evers B, Helleday T. PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites. Oncogene. 2016;35:761-70 pubmed publisher |
- immunocytochemistry; human; 1:300; fig 1
| Averbeck N, Ringel O, Herrlitz M, Jakob B, Durante M, Taucher Scholz G. DNA end resection is needed for the repair of complex lesions in G1-phase human cells. Cell Cycle. 2014;13:2509-16 pubmed publisher |
- immunocytochemistry; human; 1:2000
| Quinet A, Vessoni A, Rocha C, Gottifredi V, Biard D, Sarasin A, et al. Gap-filling and bypass at the replication fork are both active mechanisms for tolerance of low-dose ultraviolet-induced DNA damage in the human genome. DNA Repair (Amst). 2014;14:27-38 pubmed publisher |
- immunocytochemistry; human
| Lam T, Thomas L, White C, Li G, Pone E, Xu Z, et al. Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination. PLoS ONE. 2013;8:e80414 pubmed publisher |
- immunocytochemistry; human
- western blot; human
| Ouyang K, Yagle M, Matunis M, Ellis N. BLM SUMOylation regulates ssDNA accumulation at stalled replication forks. Front Genet. 2013;4:167 pubmed publisher |
- immunocytochemistry; mouse
| Schaetzlein S, Chahwan R, Avdievich E, Roa S, Wei K, Eoff R, et al. Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes. Proc Natl Acad Sci U S A. 2013;110:E2470-9 pubmed publisher |
- immunocytochemistry; human; 1:300
| Muller I, Merk B, Voss K, Averbeck N, Jakob B, Durante M, et al. Species conserved DNA damage response at the inactive human X chromosome. Mutat Res. 2013;756:30-6 pubmed publisher |
- immunocytochemistry; human; 1:500
| BURRELL R, McClelland S, Endesfelder D, Groth P, Weller M, Shaikh N, et al. Replication stress links structural and numerical cancer chromosomal instability. Nature. 2013;494:492-496 pubmed publisher |
- western blot; human; 1:500
| Soria G, Almouzni G. Differential contribution of HP1 proteins to DNA end resection and homology-directed repair. Cell Cycle. 2013;12:422-9 pubmed publisher |
| Beck H, Nähse Kumpf V, Larsen M, O Hanlon K, Patzke S, Holmberg C, et al. Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption. Mol Cell Biol. 2012;32:4226-36 pubmed |
- immunocytochemistry; human
| Sharma S, Hicks J, Chute C, Brennan J, Ahn J, Glover T, et al. REV1 and polymerase ? facilitate homologous recombination repair. Nucleic Acids Res. 2012;40:682-91 pubmed publisher |
- immunoprecipitation; human
- western blot; human
| Sun J, Oma Y, Harata M, Kono K, Shima H, Kinomura A, et al. ATM modulates the loading of recombination proteins onto a chromosomal translocation breakpoint hotspot. PLoS ONE. 2010;5:e13554 pubmed publisher |
- immunocytochemistry; human
| Kratz K, Schöpf B, Kaden S, Sendoel A, Eberhard R, Lademann C, et al. Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents. Cell. 2010;142:77-88 pubmed publisher |
- immunoprecipitation; human
- immunocytochemistry; human
- western blot; human
| Lee D, Pan Y, Kanner S, Sung P, Borowiec J, Chowdhury D. A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination. Nat Struct Mol Biol. 2010;17:365-72 pubmed publisher |
| Zuco V, Benedetti V, Zunino F. ATM- and ATR-mediated response to DNA damage induced by a novel camptothecin, ST1968. Cancer Lett. 2010;292:186-96 pubmed publisher |
- immunohistochemistry; human
- western blot; human
| Fugger K, Mistrik M, Danielsen J, Dinant C, Falck J, Bartek J, et al. Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities. J Cell Biol. 2009;186:655-63 pubmed publisher |
| Zuco V, Benedetti V, De Cesare M, Zunino F. Sensitization of ovarian carcinoma cells to the atypical retinoid ST1926 by the histone deacetylase inhibitor, RC307: enhanced DNA damage response. Int J Cancer. 2010;126:1246-55 pubmed publisher |
- western blot; human; 1:4000
| Stephan H, Concannon C, Kremmer E, Carty M, Nasheuer H. Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis. Nucleic Acids Res. 2009;37:6028-41 pubmed publisher |
- immunocytochemistry; human
| Watrin E, Peters J. The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cells. EMBO J. 2009;28:2625-35 pubmed publisher |
| Lange S, Reddy M, Vasquez K. Human HMGB1 directly facilitates interactions between nucleotide excision repair proteins on triplex-directed psoralen interstrand crosslinks. DNA Repair (Amst). 2009;8:865-72 pubmed publisher |
| Giommarelli C, Corti A, Supino R, Favini E, Paolicchi A, Pompella A, et al. Gamma-glutamyltransferase-dependent resistance to arsenic trioxide in melanoma cells and cellular sensitization by ascorbic acid. Free Radic Biol Med. 2009;46:1516-26 pubmed publisher |
- immunohistochemistry; human; 1:200
| Planchard D, Domont J, Taranchon E, Monnet I, Tredaniel J, Caliandro R, et al. The NER proteins are differentially expressed in ever smokers and in never smokers with lung adenocarcinoma. Ann Oncol. 2009;20:1257-63 pubmed publisher |
- immunohistochemistry; human; 1:200
| Barrientos K, Kendellen M, Freibaum B, Armbruster B, Etheridge K, Counter C. Distinct functions of POT1 at telomeres. Mol Cell Biol. 2008;28:5251-64 pubmed publisher |
- EMSA; human
- western blot; human
| Pisano C, Zuco V, De Cesare M, Benedetti V, Vesci L, Foderà R, et al. Intracellular accumulation and DNA damage persistence as determinants of human squamous cell carcinoma hypersensitivity to the novel camptothecin ST1968. Eur J Cancer. 2008;44:1332-40 pubmed publisher |
| Giommarelli C, Corti A, Supino R, Favini E, Paolicchi A, Pompella A, et al. Cellular response to oxidative stress and ascorbic acid in melanoma cells overexpressing gamma-glutamyltransferase. Eur J Cancer. 2008;44:750-9 pubmed publisher |
- western blot; human; 1:4000
| Braet C, Stephan H, Dobbie I, Togashi D, Ryder A, Földes Papp Z, et al. Mobility and distribution of replication protein A in living cells using fluorescence correlation spectroscopy. Exp Mol Pathol. 2007;82:156-62 pubmed |
- immunoprecipitation; human
- ELISA; human; 2 ug/ml
- western blot; human; 1:500
| Yamasaki Y, Narain S, Hernandez L, Barker T, Ikeda K, Segal M, et al. Autoantibodies against the replication protein A complex in systemic lupus erythematosus and other autoimmune diseases. Arthritis Res Ther. 2006;8:R111 pubmed |
- immunocytochemistry; human
- western blot; human
| Rossi R, Lidonnici M, Soza S, Biamonti G, Montecucco A. The dispersal of replication proteins after Etoposide treatment requires the cooperation of Nbs1 with the ataxia telangiectasia Rad3-related/Chk1 pathway. Cancer Res. 2006;66:1675-83 pubmed |
| Zuco V, Zanchi C, Lanzi C, Beretta G, Supino R, Pisano C, et al. Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA damage response. Neoplasia. 2005;7:667-77 pubmed |
| Hossain M, Lin Y, Driscoll G, Li J, McMahon A, Matos J, et al. APE2 Is a General Regulator of the ATR-Chk1 DNA Damage Response Pathway to Maintain Genome Integrity in Pancreatic Cancer Cells. Front Cell Dev Biol. 2021;9:738502 pubmed publisher |
| Ju M, Shin K, Lee J, Khim K, A Lee E, Ra J, et al. NSMF promotes the replication stress-induced DNA damage response for genome maintenance. Nucleic Acids Res. 2021;49:5605-5622 pubmed publisher |
| Jegadesan N, Branzei D. DDX11 loss causes replication stress and pharmacologically exploitable DNA repair defects. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher |
| Genois M, Gagné J, Yasuhara T, Jackson J, Saxena S, Langelier M, et al. CARM1 regulates replication fork speed and stress response by stimulating PARP1. Mol Cell. 2021;81:784-800.e8 pubmed publisher |
| Lin Y, Raj J, Li J, Ha A, Hossain M, Richardson C, et al. APE1 senses DNA single-strand breaks for repair and signaling. Nucleic Acids Res. 2020;48:1925-1940 pubmed publisher |
| Moiseeva T, Hood B, Schamus S, O Connor M, Conrads T, Bakkenist C. ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1. Nat Commun. 2017;8:1392 pubmed publisher |
| Taglialatela A, Alvarez S, Leuzzi G, Sannino V, Ranjha L, Huang J, et al. Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers. Mol Cell. 2017;68:414-430.e8 pubmed publisher |
| Dubois J, Yates M, Gaudreau Lapierre A, Clement G, Cappadocia L, Gaudreau L, et al. A phosphorylation-and-ubiquitylation circuitry driving ATR activation and homologous recombination. Nucleic Acids Res. 2017;45:8859-8872 pubmed publisher |
| Nguyen H, Yadav T, Giri S, Saez B, Graubert T, Zou L. Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1. Mol Cell. 2017;65:832-847.e4 pubmed publisher |
| Hu R, Wang E, Peng G, Dai H, Lin S. Zinc finger protein 668 interacts with Tip60 to promote H2AX acetylation after DNA damage. Cell Cycle. 2013;12:2033-41 pubmed publisher |
| Ricke R, Bielinsky A. Mcm10 regulates the stability and chromatin association of DNA polymerase-alpha. Mol Cell. 2004;16:173-85 pubmed |
| Zuco V, Zanchi C, Cassinelli G, Lanzi C, Supino R, Pisano C, et al. Induction of apoptosis and stress response in ovarian carcinoma cell lines treated with ST1926, an atypical retinoid. Cell Death Differ. 2004;11:280-9 pubmed |
| Sukhodolets K, Hickman A, Agarwal S, Sukhodolets M, Obungu V, Novotny E, et al. The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene. Mol Cell Biol. 2003;23:493-509 pubmed |
