Caspase 3 Monoclonal Antibody (3CSP03) | Invitrogen MA1-26415 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Caspase 3 Monoclonal Antibody (3CSP03)

catalog :

MA1-26415

quantity :

500 µL

price :

US 475.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3CSP03

reactivity :

human, rat

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 15

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; rat	Kilicdag H, Daglioglu Y, Erdogan S, Zorludemir S. Effects of caffeine on neuronal apoptosis in neonatal hypoxic-ischemic brain injury. J Matern Fetal Neonatal Med. 2014;27:1470-5 pubmed publisher
immunohistochemistry; human; 1:200	Mitra A, Castelao J, Hawes D, Tsao Wei D, Jiang X, Shi S, et al. Combination of molecular alterations and smoking intensity predicts bladder cancer outcome: a report from the Los Angeles Cancer Surveillance Program. Cancer. 2013;119:756-65 pubmed publisher
immunohistochemistry; human; 1:300	Winter J, Tang L, Klimstra D, Brennan M, Brody J, Rocha F, et al. A novel survival-based tissue microarray of pancreatic cancer validates MUC1 and mesothelin as biomarkers. PLoS ONE. 2012;7:e40157 pubmed publisher
immunohistochemistry; human; 1:50	Mattila R, Rautava J, SyrjÃ¤nen S. Human papillomavirus in oral atrophic lichen planus lesions. Oral Oncol. 2012;48:980-984 pubmed publisher
immunohistochemistry; rat; 1:100	Ozcura F, Dündar S, Cetin E, Beder N, Dundar M. Effects of estrogen replacement therapy on apoptosis and vascular endothelial growth factor expression in ocular surface epithelial cells: An experimental study. Int J Ophthalmol. 2012;5:64-8 pubmed publisher
immunohistochemistry; human; 1:300	Kılıçay E, Demirbilek M, Turk M, Güven E, Hazer B, Denkbas E. Preparation and characterization of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHX) based nanoparticles for targeted cancer therapy. Eur J Pharm Sci. 2011;44:310-20 pubmed publisher
immunohistochemistry; human; 1:50	Filis K, Kavantzas N, Isopoulos T, Antonakis P, Sigalas P, Vavouranakis E, et al. Increased vein wall apoptosis in varicose vein disease is related to venous hypertension. Eur J Vasc Endovasc Surg. 2011;41:533-9 pubmed publisher
immunohistochemistry; human	Ha K, Kim B, Kim K, Oh I, Seo J. Apoptosis in the sequestrated nucleus pulposus compared to the remaining nucleus pulposus in the same patient. Spine (Phila Pa 1976). 2011;36:683-9 pubmed publisher
immunohistochemistry; human; 1:50	Mattila R, Syrjanen S. Caspase cascade pathways in apoptosis of oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;110:618-23 pubmed publisher
immunohistochemistry; human; 1:70	Cho S, Lee J, Cho S, Yoon K, Park S, Lee W, et al. Epigenetic methylation and expression of caspase 8 and survivin in hepatocellular carcinoma. Pathol Int. 2010;60:203-11 pubmed publisher
immunohistochemistry; human; 1:300	Papay J, Krenacs T, Moldvay J, Stelkovics E, Furak J, Molnar B, et al. Immunophenotypic profiling of nonsmall cell lung cancer progression using the tissue microarray approach. Appl Immunohistochem Mol Morphol. 2007;15:19-30 pubmed
immunohistochemistry - paraffin section; human immunohistochemistry; human; 1:50	Yoo J, Jung J, Lee M, Seo K, Shim B, Kim S, et al. Immunohistochemical analysis of non-small cell lung cancer: correlation with clinical parameters and prognosis. J Korean Med Sci. 2007;22:318-25 pubmed
immunohistochemistry; human	Blazquez S, Sirvent J, Olona M, Aguilar C, Pelegri A, Garcia J, et al. Caspase-3 and caspase-6 in ductal breast carcinoma: a descriptive study. Histol Histopathol. 2006;21:1321-9 pubmed publisher
immunohistochemistry; human; 1:200	Vital Reyes V, Rodríguez Burford C, Chhieng D, Alvarado Cabrero I, Reyes Fuentes A, Grizzle W. Ovarian expression of markers associated with proliferation or apoptosis in women with diminished ovarian reserve. Fertil Steril. 2006;86:176-85 pubmed
immunohistochemistry; human	Plataki M, Koutsopoulos A, Darivianaki K, Delides G, Siafakas N, Bouros D. Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosis. Chest. 2005;127:266-74 pubmed

product information

Product Type :

Antibody

Product Name :

Caspase 3 Monoclonal Antibody (3CSP03)

Catalog # :

MA1-26415

Quantity :

500 µL

Price :

US 475.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:25-1:75

Species :

Human

Clone :

3CSP03

Isotype :

IgG2a

Storage :

4° C

Description :

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Immunogen :

Recombinant, full length human protein.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:25-1:75

Aliases :

A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mldy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein