RET Monoclonal Antibody (RET01) | Invitrogen MA1-26379 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RET Monoclonal Antibody (RET01)

catalog :

MA1-26379

quantity :

500µL

price :

US 425.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

RET01

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:25	Styring E, Seinen J, Dominguez Valentin M, Domanski H, Jonsson M, von Steyern F, et al. Key roles for MYC, KIT and RET signaling in secondary angiosarcomas. Br J Cancer. 2014;111:407-12 pubmed publisher
immunocytochemistry; human; 1:50 immunohistochemistry; human; 1:50	Luesma M, Cantarero I, Álvarez Dotu J, Santander S, Junquera C. New insights into c-Ret signalling pathway in the enteric nervous system and its relationship with ALS. Biomed Res Int. 2014;2014:328348 pubmed publisher
immunohistochemistry; human	Bentzien F, Zuzow M, Heald N, Gibson A, Shi Y, Goon L, et al. In vitro and in vivo activity of cabozantinib (XL184), an inhibitor of RET, MET, and VEGFR2, in a model of medullary thyroid cancer. Thyroid. 2013;23:1569-77 pubmed publisher
	Powers J, Brachold J, Tischler A. Ret protein expression in adrenal medullary hyperplasia and pheochromocytoma. Endocr Pathol. 2003;14:351-61 pubmed

product information

Product Type :

Antibody

Product Name :

RET Monoclonal Antibody (RET01)

Catalog # :

MA1-26379

Quantity :

500µL

Price :

US 425.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Frozen): 1:10-1:20, Immunohistochemistry (Paraffin): 1:10-1:20

Species :

Human

Clone :

RET01

Isotype :

IgG1

Storage :

4° C, do not freeze

Description :

This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. , ,

Immunogen :

Recombinant protein containing the extreme C-terminal cytoplasmic region of the human ret oncoprotein.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Frozen): 1:10-1:20, Immunohistochemistry (Paraffin): 1:10-1:20

Aliases :

CDHF12, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1, RET51