CD31 Monoclonal Antibody (WM59) | Invitrogen MA1-26196 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD31 Monoclonal Antibody (WM59)

catalog :

MA1-26196

quantity :

100 µg

price :

US 496.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

WM59

reactivity :

crab eating macaque, human, mouse, rat, rhesus macaque

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...; fig 3d	James K, Cosway E, LUCAS B, White A, Parnell S, Carvalho Gaspar M, et al. Endothelial cells act as gatekeepers for LTβR-dependent thymocyte emigration. J Exp Med. 2018;215:2984-2993 pubmed publisher
flow cytometry; human; loading ...; tbl 1	Monsuur H, Weijers E, Niessen F, Gefen A, Koolwijk P, Gibbs S, et al. Extensive Characterization and Comparison of Endothelial Cells Derived from Dermis and Adipose Tissue: Potential Use in Tissue Engineering. PLoS ONE. 2016;11:e0167056 pubmed publisher
flow cytometry; human; tbl 2	Ghebeh H, Sleiman G, Manogaran P, Al Mazrou A, Barhoush E, Al Mohanna F, et al. Profiling of normal and malignant breast tissue show CD44high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers. BMC Cancer. 2013;13:289 pubmed publisher
immunohistochemistry; rat	Alcala M, Shade C, Uh H, Kwan S, Bischof M, Thompson Z, et al. Preferential accumulation within tumors and in vivo imaging by functionalized luminescent dendrimer lanthanide complexes. Biomaterials. 2011;32:9343-52 pubmed publisher
immunohistochemistry; rat	Alcala M, Kwan S, Shade C, Lang M, Uh H, Wang M, et al. Luminescence targeting and imaging using a nanoscale generation 3 dendrimer in an in vivo colorectal metastatic rat model. Nanomedicine. 2011;7:249-58 pubmed publisher
	Zhao W, Wang L, Yang J, Chen X, Guo X, Xu K, et al. Endothelial cell-derived MMP19 promotes pulmonary fibrosis by inducing E(nd)MT and monocyte infiltration. Cell Commun Signal. 2023;21:56 pubmed publisher
	Lu G, Xu Y, Liu Q, Chen M, Sun H, Wang P, et al. An instantly fixable and self-adaptive scaffold for skull regeneration by autologous stem cell recruitment and angiogenesis. Nat Commun. 2022;13:2499 pubmed publisher
	Sargent J, ROBERTS V, D Souza K, Wright A, Gaffney J, Frias A. Micro-anatomic alterations of the placenta in a non-human primate model of gestational protein-restriction. PLoS ONE. 2020;15:e0235840 pubmed publisher
	Sargent J, Roberts V, Gaffney J, Frias A. Clarification and confocal imaging of the nonhuman primate placental micro-anatomy. Biotechniques. 2019;66:79-84 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD31 Monoclonal Antibody (WM59)

Catalog # :

MA1-26196

Quantity :

100 µg

Price :

US 496.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Cynomolgus Monkey, Human, Mouse, Non-human primate, Rhesus Monkey

Applications :

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:50-1:100, Immunohistochemistry - Free Floating: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent

Species :

Cynomolgus Monkey, Human, Mouse, Non-human primate, Rhesus Monkey

Clone :

WM59

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

Immunogen :

Human CD31

Format :

Liquid

Applications w/Dilutions :

Aliases :

C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

more info or order :

Invitrogen product webpage