CD15 Monoclonal Antibody (MMA) | Invitrogen MA1-25911 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD15 Monoclonal Antibody (MMA)

catalog :

MA1-25911

quantity :

1 mL

price :

US 484

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MMA

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human	Lorenzi L, Tabellini G, Vermi W, Moratto D, Porta F, Notarangelo L, et al. Occurrence of nodular lymphocyte-predominant hodgkin lymphoma in hermansky-pudlak type 2 syndrome is associated to natural killer and natural killer T cell defects. PLoS ONE. 2013;8:e80131 pubmed publisher
immunocytochemistry; human; 1:100	Buttler D, Mai J, Ashwell K, Andressen C. Clonogenic CD15 immunoreactive radial glial cells from the developing human lateral ganglionic eminence. Curr Pharm Biotechnol. 2013;14:29-35 pubmed
immunohistochemistry; human	Maounis N, Chorti M, Legaki S, Ellina E, Emmanouilidou A, Demonakou M, et al. Metastasis to the breast from an adenocarcinoma of the lung with extensive micropapillary component: a case report and review of the literature. Diagn Pathol. 2010;5:82 pubmed publisher
immunocytochemistry; human; 1:100	Boer K, Jansen F, Nellist M, Redeker S, van den Ouweland A, Spliet W, et al. Inflammatory processes in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex. Epilepsy Res. 2008;78:7-21 pubmed
immunohistochemistry; human; 1:100	Ravizza T, Gagliardi B, Noe F, Boer K, Aronica E, Vezzani A. Innate and adaptive immunity during epileptogenesis and spontaneous seizures: evidence from experimental models and human temporal lobe epilepsy. Neurobiol Dis. 2008;29:142-60 pubmed
	RadonjiÄ‡ N, Memi F, Ortega J, Glidden N, Zhan H, Zecevic N. The Role of Sonic Hedgehog in the Specification of Human Cortical Progenitors In Vitro. Cereb Cortex. 2016;26:131-43 pubmed publisher
	Ziegler A, Chidambaram S, Forbes B, Wood T, Levison S. Insulin-like growth factor-II (IGF-II) and IGF-II analogs with enhanced insulin receptor-a binding affinity promote neural stem cell expansion. J Biol Chem. 2014;289:4626-33 pubmed publisher
	Buono K, Vadlamuri D, Gan Q, Levison S. Leukemia inhibitory factor is essential for subventricular zone neural stem cell and progenitor homeostasis as revealed by a novel flow cytometric analysis. Dev Neurosci. 2012;34:449-62 pubmed publisher
	Tulunay O, Gogus C, Baltaci S, Bulut S. Clear cell adenocarcinoma of the tunica vaginalis of the testis with an adjacent uterus-like tissue. Pathol Int. 2004;54:641-7 pubmed

product information

Product Type :

Antibody

Product Name :

CD15 Monoclonal Antibody (MMA)

Catalog # :

MA1-25911

Quantity :

1 mL

Price :

US 484

Clonality :

Monoclonal

Purity :

IgM

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunohistochemistry (Paraffin): 1:50-1:100

Species :

Human, Mouse

Clone :

MMA

Isotype :

IgM

Storage :

4° C, do not freeze

Description :

CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.

Immunogen :

U937 histiocytic cell line.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50-1:100

Aliases :

FUTIV; Lewis X; SSEA-1

more info or order :

Invitrogen product webpage