TNFRSF14 Monoclonal Antibody (Laury-1) | Invitrogen MA1-25844 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TNFRSF14 Monoclonal Antibody (Laury-1)

catalog :

MA1-25844

quantity :

50 µg

price :

US 524

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

Laury-1

reactivity :

human

application :

immunoprecipitation, flow cytometry

product information

Product Type :

Antibody

Product Name :

TNFRSF14 Monoclonal Antibody (Laury-1)

Catalog # :

MA1-25844

Quantity :

50 µg

Price :

US 524

Clonality :

Monoclonal

Purity :

Size-exclusion - Gel filtration

Host :

Rat

Reactivity :

Human

Applications :

Flow Cytometry: 1:1,000, Immunoprecipitation: 1:200

Species :

Human

Clone :

Laury-1

Isotype :

IgG2a

Storage :

4° C

Description :

TNFRSF14 is a member of the TNF-receptor superfamily. TNFRSF14 was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to TNFRSF14 has been shown to be part of the viral entry mechanism. The cytoplasmic region of TNFRSF14 was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. Activation of the signal transduction pathway involving TNFRSF14 in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these TNFRSF14 variants have not been determined.

Immunogen :

Fusion protein corresponding to the extracellular domain (residues 39-200) of human TNFRSF14, fused to the Fc portion of human IgG1.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:1,000, Immunoprecipitation: 1:200

Aliases :

Atar; CD270; CD40-like protein; herpes virus entry mediator; herpes virus entry mediator A; Herpesvirus entry mediator A; HGNC:11912; HVEA; Hvem; LIGHTR; RP3-395M20.6; sCD2710; TNF receptor superfamily member 14; Tnfrs14; TNFRSF14; TR2; tumo; Tumor necrosis factor receptor superfamily member 14; tumor necrosis factor receptor superfamily, member 14; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); Tumor necrosis factor receptor-like 2; tumor necrosis factor receptor-like gene2; UNQ329/PRO509