TOLLIP Monoclonal Antibody (Kimmy-2) | Invitrogen MA1-25840 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TOLLIP Monoclonal Antibody (Kimmy-2)

catalog :

MA1-25840

quantity :

50 ug

price :

US 524.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Kimmy-2

The same clone is also sold as:

Santa Cruz Biotechnology: sc-59720

reactivity :

human, mouse

application :

western blot, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

TOLLIP Monoclonal Antibody (Kimmy-2)

Catalog # :

MA1-25840

Quantity :

50 ug

Price :

US 524.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunoprecipitation: Assay-dependent, Western Blot: 1 ug/mL

Species :

Human, Mouse

Clone :

Kimmy-2

Isotype :

IgG1

Storage :

4 C

Description :

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation. This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.

Immunogen :

Recombinant fragment corresponding to residues 1-274 of mouse Tollip.

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: Assay-dependent, Western Blot: 1 ug/mL

Aliases :

4930403G24Rik; 4931428G15Rik; adapter protein; EMBL:AAI33068.1}; FLJ33531; IL-1RAcPIP; toll interacting protein; toll-interacting protein; TOLLIP; tollip {ECO:0000312