APRIL Monoclonal Antibody (Aprily-1) | Invitrogen MA1-25839 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

APRIL Monoclonal Antibody (Aprily-1)

catalog :

MA1-25839

quantity :

50 µg

price :

US 524

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Aprily-1

reactivity :

human

application :

western blot, flow cytometry, blocking or activating experiments

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; loading ...; fig 2c	Tai Y, Lin L, Xing L, Cho S, Yu T, Acharya C, et al. APRIL signaling via TACI mediates immunosuppression by T regulatory cells in multiple myeloma: therapeutic implications. Leukemia. 2019;33:426-438 pubmed publisher

product information

Product Type :

Antibody

Product Name :

APRIL Monoclonal Antibody (Aprily-1)

Catalog # :

MA1-25839

Quantity :

50 µg

Price :

US 524

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 10 µg/mL, Western Blot: 2 µg/mL

Species :

Human

Clone :

Aprily-1

Isotype :

IgG1

Storage :

4° C

Description :

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.

Immunogen :

Recombinant fragment corresponding to residues 93-233 of human APRIL, expressed in bacteria.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 10 µg/mL, Western Blot: 2 µg/mL

Aliases :

2310026N09Rik; A proliferation-inducing ligand; APRIL; CD256; TALL2; TALL-2; TNF- and APOL-related leukocyte expressed ligand 2; TNF-related death ligand 1; Tnfsf13; TNLG7B; Trdl1; TRDL-1; tumor necrosis factor (ligand) superfamily, member 13; tumor necrosis factor ligand 7B; tumor necrosis factor ligand superfamily member 13; tumor necrosis factor superfamily member 13; tumor necrosis factor-like protein ZTNF2; tumor necrosis factor-related death ligand-1; UNQ383/PRO715; ZTNF2

more info or order :

Invitrogen product webpage