Metallothionein Monoclonal Antibody (UC1MT) | Invitrogen MA1-25479 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Metallothionein Monoclonal Antibody (UC1MT)

catalog :

MA1-25479

quantity :

50 µg

price :

US 496.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

UC1MT

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; fig 9a	Whitson J, Zhang X, Medvedovic M, Chen J, Wei Z, Monnier V, et al. Transcriptome of the GSH-Depleted Lens Reveals Changes in Detoxification and EMT Signaling Genes, Transport Systems, and Lipid Homeostasis. Invest Ophthalmol Vis Sci. 2017;58:2666-2684 pubmed publisher
	Yao C, Cao Y, Wang D, Lv Y, Liu Y, Gu X, et al. Single-cell sequencing reveals microglia induced angiogenesis by specific subsets of endothelial cells following spinal cord injury. FASEB J. 2022;36:e22393 pubmed publisher
	Migliaccio V, Sica R, Scudiero R, Simoniello P, Putti R, Lionetti L. Physiological Adaptation to Simultaneous Chronic Exposure to High-Fat Diet and Dichlorodipheniletylhene (DDE) in Wistar Rat Testis. Cells. 2019;8: pubmed publisher
	Kepinska M, Kizek R, Milnerowicz H. Metallothionein and Superoxide Dismutase-Antioxidative Protein Status in Fullerene-Doxorubicin Delivery to MCF-7 Human Breast Cancer Cells. Int J Mol Sci. 2018;19: pubmed publisher
	Liu S, Yuan J, Yue W, Bi Y, Shen X, Gao J, et al. GCN2 deficiency protects against high fat diet induced hepatic steatosis and insulin resistance in mice. Biochim Biophys Acta Mol Basis Dis. 2018;1864:3257-3267 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Metallothionein Monoclonal Antibody (UC1MT)

Catalog # :

MA1-25479

Quantity :

50 µg

Price :

US 496.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Equine, Fish, Human, Mouse, Rabbit, Rat

Applications :

Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:1,000

Species :

Equine, Fish, Human, Mouse, Rabbit, Rat

Clone :

UC1MT

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-ordinate metal ions using mercaptide linkages. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. MT1A (Metallothionein 1A) is a Protein Coding gene. Diseases associated with MT1A include Menkes Disease and Deficiency Anemia. Among its related pathways are Metal ion SLC transporters and Cellular responses to stimuli. An important paralog of this gene is MT2A.

Immunogen :

Full length protein from cross linked rabbit liver MT1 and MT2.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:1,000

Aliases :

Metallothionein; Metallothionein-1

more info or order :

Invitrogen product webpage