beta-1,2 Adaptin Monoclonal Antibody (100/1) | Invitrogen MA1-25065 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

beta-1,2 Adaptin Monoclonal Antibody (100/1)

catalog :

MA1-25065

quantity :

100 uL

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

100/1

The same clone is also sold as:

Santa Cruz Biotechnology: sc-58226

reactivity :

human, rat, bovine

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 4

Reference
Almeida Souza L, Frank R, García Nafría J, Colussi A, Gunawardana N, Johnson C, et al. A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits. Cell. 2018;174:325-337.e14 pubmed publisher
Mulay A, Akram K, Williams D, Armes H, Russell C, Hood D, et al. An in vitro model of murine middle ear epithelium. Dis Model Mech. 2016;9:1405-1417 pubmed
Chang M, Mallet W, Mostov K, Brodsky F. Adaptor self-aggregation, adaptor-receptor recognition and binding of alpha-adaptin subunits to the plasma membrane contribute to recruitment of adaptor (AP2) components of clathrin-coated pits. EMBO J. 1993;12:2169-80 pubmed
Wong D, Brodsky F. 100-kD proteins of Golgi- and trans-Golgi network-associated coated vesicles have related but distinct membrane binding properties. J Cell Biol. 1992;117:1171-9 pubmed

product information

Product Type :

Antibody

Product Name :

beta-1,2 Adaptin Monoclonal Antibody (100/1)

Catalog # :

MA1-25065

Quantity :

100 uL

Price :

US 474.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Bovine, Human, Rat

Applications :

Immunocytochemistry: 1:250, Immunoprecipitation: Assay-dependent, Western Blot: 1:200

Species :

Bovine, Human, Rat

Clone :

100/1

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.

Immunogen :

AP2 adaptor from bovine brain.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:250, Immunoprecipitation: Assay-dependent, Western Blot: 1:200

Aliases :

adapter-related protein complex 1 subunit beta-1; adapter-related protein complex 2 beta subunit; adapter-related protein complex 2 subunit beta; adaptin, beta 2 (beta); adaptor protein complex AP-1 subunit beta-1; adaptor protein complex AP-1, beta 1 subunit; adaptor protein complex AP-2 subunit beta; adaptor related protein complex 1 beta 1 subunit; adaptor related protein complex 1 subunit beta 1; adaptor related protein complex 2 beta 1 subunit; adaptor related protein complex 2 subunit beta 1; adaptor related protein complex 2, beta 1 subunit; adaptor-related protein complex 1 beta 1 subunit; adaptor-related protein complex 1 subunit beta-1; adaptor-related protein complex 1, beta 1 subunit; adaptor-related protein complex 2 subunit beta; adaptor-related protein complex 2, beta 1 subunit; adaptor-related protein complex AP-1 beta 1 subunit; ADTB1; ADTB2; AP-1 complex subunit beta-1; AP105A; AP105B; AP1B1; AP-2 complex subunit beta; AP2B1; AP2-BETA; BAM22; beta adaptin; beta-1-adaptin; beta1-adaptin; Beta-2-adaptin; beta2-adaptin; beta-adaptin; Beta-adaptin 1; beta-prime-adaptin; Clapb1; CLAPB2; Clathrin assembly protein complex 1 beta large chain; clathrin assembly protein complex 2 beta large chain; clathrin-associated / assembly / adaptor protein, large, beta 1; clathrin-associated/assembly/adaptor protein, large, beta 1; golgi adaptor HA1/AP1 adaptin beta subunit; MGC128441 protein; plasma membrane adaptor HA2/AP2 adaptin beta subunit; plasma membrane adaptor HA2/AP2 adaptor beta subunit; testicular tissue protein Li 22