MAP2 Monoclonal Antibody (AP20) | Invitrogen MA1-25044 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MAP2 Monoclonal Antibody (AP20)

catalog :

MA1-25044

quantity :

50 µL

price :

US 450.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AP20

reactivity :

guinea pig, human, mouse, rat, bovine, Xenopus laevis

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s7a	Tamaki Y, Shodai A, Morimura T, Hikiami R, Minamiyama S, Ayaki T, et al. Elimination of TDP-43 inclusions linked to amyotrophic lateral sclerosis by a misfolding-specific intrabody with dual proteolytic signals. Sci Rep. 2018;8:6030 pubmed publisher
immunohistochemistry - paraffin section; human; 1:400; loading ...; fig s2a	Yarchoan M, Toledo J, Lee E, Arvanitakis Z, Kazi H, Han L, et al. Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies. Acta Neuropathol. 2014;128:679-89 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:6000; fig 7	Karasinska J, de Haan W, Franciosi S, Ruddle P, Fan J, Kruit J, et al. ABCA1 influences neuroinflammation and neuronal death. Neurobiol Dis. 2013;54:445-55 pubmed publisher
immunocytochemistry; human	Yasukawa T, Bhatt S, Takeuchi T, Kawauchi J, Takahashi H, Tsutsui A, et al. Transcriptional elongation factor elongin A regulates retinoic acid-induced gene expression during neuronal differentiation. Cell Rep. 2012;2:1129-36 pubmed publisher
immunohistochemistry; mouse; 1:100	Okae H, Iwakura Y. Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice. Dev Dyn. 2010;239:1089-101 pubmed publisher
immunohistochemistry; guinea pig; 1:100	Kan R, Pleva C, Hamilton T, Petrali J. Immunolocalization of MAP-2 in routinely formalin-fixed, paraffin-embedded guinea pig brain sections using microwave irradiation: a comparison of different combinations of antibody clones and antigen retrieval buffer solutions. Microsc Microanal. 2005;11:175-80 pubmed
	Hook C, Puche A. Bulbar projecting subcortical GABAergic neurons send collateral branches extensively and selectively to primary olfactory cortical regions. J Comp Neurol. 2023;531:451-460 pubmed publisher
	Quintero Espinosa D, Soto Mercado V, Quintero Quinchia C, Mendivil Perez M, Velez Pardo C, Jimenez Del Rio M. Latent Tri-lineage Potential of Human Menstrual Blood-Derived Mesenchymal Stromal Cells Revealed by Specific In Vitro Culture Conditions. Mol Neurobiol. 2021;58:5194-5209 pubmed publisher
	Soto Mercado V, Mendivil Perez M, Velez Pardo C, Lopera F, Jimenez Del Rio M. Cholinergic-like neurons carrying PSEN1 E280A mutation from familial Alzheimer's disease reveal intraneuronal sAPPβ fragments accumulation, hyperphosphorylation of TAU, oxidative stress, apoptosis and Ca2+ dysregulation: Therapeutic implications. PLoS ONE. 2020;15:e0221669 pubmed publisher
	Kruminis Kaszkiel E, Osowski A, Bejer Olenska E, Dziekoński M, Wojtkiewicz J. Differentiation of Human Mesenchymal Stem Cells from Wharton's Jelly Towards Neural Stem Cells Using A Feasible and Repeatable Protocol. Cells. 2020;9: pubmed publisher
	Jiang S, Xu W, Emery A, Gerfen C, Eiden M, Eiden L. NCS-Rapgef2, the Protein Product of the Neuronal Rapgef2 Gene, Is a Specific Activator of D1 Dopamine Receptor-Dependent ERK Phosphorylation in Mouse Brain. Eneuro. 2017;4: pubmed publisher
	Belachew S, Chittajallu R, Aguirre A, Yuan X, Kirby M, Anderson S, et al. Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons. J Cell Biol. 2003;161:169-86 pubmed

product information

Product Type :

Antibody

Product Name :

MAP2 Monoclonal Antibody (AP20)

Catalog # :

MA1-25044

Quantity :

50 µL

Price :

US 450.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Amphibian, Avian, Bovine, Human, Mouse, Rat, Xenopus laevis

Applications :

Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:500

Species :

Amphibian, Avian, Bovine, Human, Mouse, Rat, Xenopus laevis

Clone :

AP20

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer's Disease (AD).

Immunogen :

Bovine protein.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:500

Aliases :

a730034c02; AC091465.1; DKFZp686I2148; G1-397-34; MAP 2; Map2; MAP-2; map2.S; map2a; map-2a; map2ab; MAP2B; MAP2C; MAP2R; microtubule associated protein 2; microtubule associated protein 2 S homeolog; microtubule associated protein 2; microtubule-associated protein 2; microtubule associated protein 2C; microtubule-associated protein 2; microtubule-associated protein-2; Mtap2; Mtap-2; OTTHUMP00000163916; OTTHUMP00000208143; repro4; XELAEV_18047318mg; xmap2

more info or order :

Invitrogen product webpage