| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; domestic sheep; loading ...; fig 7b
| van Gorp C, de Lange I, Massy K, Kessels L, Jobe A, Cleutjens J, et al. Intestinal Goblet Cell Loss during Chorioamnionitis in Fetal Lambs: Mechanistic Insights and Postnatal Implications. Int J Mol Sci. 2021;22: pubmed publisher |
- immunocytochemistry; human; loading ...; fig s1b
| Fletcher R, Tong J, Risnik D, Leibowitz B, Wang Y, Concha Benavente F, et al. Non-steroidal anti-inflammatory drugs induce immunogenic cell death in suppressing colorectal tumorigenesis. Oncogene. 2021;40:2035-2050 pubmed publisher |
- western blot; human; fig 3e
| Fauster A, Rebsamen M, Willmann K, César Razquin A, Girardi E, Bigenzahn J, et al. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2019;26:1138-1155 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5b
| Skopková M, Hennig F, Shin B, Turner C, Stanikova D, Brennerova K, et al. EIF2S3 Mutations Associated with Severe X-Linked Intellectual Disability Syndrome MEHMO. Hum Mutat. 2017;38:409-425 pubmed publisher |
- western blot; mouse; loading ...; fig 4c
| Mukhopadhyay C, Triplett A, Bargar T, HECKMAN C, Wagner K, Naramura M. Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation. Proc Natl Acad Sci U S A. 2016;113:E8228-E8237 pubmed publisher |
- western blot; rat; loading ...; fig 6a
| Cóppola Segovia V, Cavarsan C, Maia F, Ferraz A, Nakao L, Lima M, et al. ER Stress Induced by Tunicamycin Triggers ?-Synuclein Oligomerization, Dopaminergic Neurons Death and Locomotor Impairment: a New Model of Parkinson's Disease. Mol Neurobiol. 2017;54:5798-5806 pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 8c
| Duan H, Lee J, Moon S, Arora D, Li Y, Lim H, et al. Discovery, Synthesis, and Evaluation of 2,4-Diaminoquinazolines as a Novel Class of Pancreatic ?-Cell-Protective Agents against Endoplasmic Reticulum (ER) Stress. J Med Chem. 2016;59:7783-800 pubmed publisher |
- immunohistochemistry; mouse; 1:200; fig 6
- western blot; mouse; 1:200; fig 6
| Jiang M, Liu L, He X, Wang H, Lin W, Wang H, et al. Regulation of PERK-eIF2? signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes. Nat Commun. 2016;7:12185 pubmed publisher |
| Shruthi K, Reddy S, Reddy P, Shivalingam P, Harishankar N, Reddy G. Amelioration of neuronal cell death in a spontaneous obese rat model by dietary restriction through modulation of ubiquitin proteasome system. J Nutr Biochem. 2016;33:73-81 pubmed publisher |
- immunohistochemistry; mouse; 1:100; fig 7
- western blot; mouse; 1:200; fig 7
| Hudish L, Galati D, Ravanelli A, Pearson C, Huang P, Appel B. miR-219 regulates neural progenitors by dampening apical Par protein-dependent Hedgehog signaling. Development. 2016;143:2292-304 pubmed publisher |
- western blot; human; 1:500; fig 2
| Zheng X, Xu J, Chen X, Li W, Wang T. Attenuation of oxygen fluctuation-induced endoplasmic reticulum stress in human lens epithelial cells. Exp Ther Med. 2015;10:1883-1887 pubmed |
- western blot; mouse; fig 4
| Antonucci L, Fagman J, Kim J, Todoric J, Gukovsky I, Mackey M, et al. Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress. Proc Natl Acad Sci U S A. 2015;112:E6166-74 pubmed publisher |
- immunohistochemistry - paraffin section; domestic rabbit; fig 2d-f
| Kruzliak P, Sabo J, Zulli A. Endothelial endoplasmic reticulum and nitrative stress in endothelial dysfunction in the atherogenic rabbit model. Acta Histochem. 2015;117:762-6 pubmed publisher |
- western blot; human; 1:2000; fig 1.a,b
| Treacy Abarca S, Mukherjee S. Legionella suppresses the host unfolded protein response via multiple mechanisms. Nat Commun. 2015;6:7887 pubmed publisher |
- western blot; human; 1:1000; fig 3c
| Duan H, Li Y, Lim H, Wang W. Identification of 5-nitrofuran-2-amide derivatives that induce apoptosis in triple negative breast cancer cells by activating C/EBP-homologous protein expression. Bioorg Med Chem. 2015;23:4514-21 pubmed publisher |
- western blot; human; 1:1000; fig s2b
- western blot; mouse; fig 3g
| Das I, Krzyzosiak A, Schneider K, Wrabetz L, D Antonio M, Barry N, et al. Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit. Science. 2015;348:239-42 pubmed publisher |
| Way S, Podojil J, Clayton B, Zaremba A, Collins T, Kunjamma R, et al. Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic. Nat Commun. 2015;6:6532 pubmed publisher |
- western blot; human; 1:100; fig 1
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| Myers S, Andres K, Hagg T, Whittemore S. CD36 deletion improves recovery from spinal cord injury. Exp Neurol. 2014;256:25-38 pubmed publisher |
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- immunocytochemistry; rat; 1:1000
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- immunocytochemistry; human
- western blot; human
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- western blot; mouse; 1:1,000
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| Lee Y, Cevallos R, Jan E. An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation. J Biol Chem. 2009;284:6661-73 pubmed publisher |
| Lu A, Hiltunen M, Romano D, Soininen H, Hyman B, Bertram L, et al. Effects of ubiquilin 1 on the unfolded protein response. J Mol Neurosci. 2009;38:19-30 pubmed publisher |
| Gramolini A, Kislinger T, Alikhani Koopaei R, Fong V, Thompson N, Isserlin R, et al. Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses. Mol Cell Proteomics. 2008;7:519-33 pubmed |
| Sutandy F, G xf6 xdf ner I, Tascher G, M xfc nch C. A cytosolic surveillance mechanism activates the mitochondrial UPR. Nature. 2023;618:849-854 pubmed publisher |
| Morales C, Fernández M, Ferrer R, Raimunda D, Carrer D, Bollo M. Ursodeoxycholic Acid Binds PERK and Ameliorates Neurite Atrophy in a Cellular Model of GM2 Gangliosidosis. Int J Mol Sci. 2023;24: pubmed publisher |
| Rogachev V, Goltyaev M, Varlamova E, Turovsky E. Molecular Mechanisms of the Cytotoxic Effect of Recombinant Selenoprotein SELENOM on Human Glioblastoma Cells. Int J Mol Sci. 2023;24: pubmed publisher |
| Luan W, Wright A, Brown Wright H, Le S, San Gil R, Madrid San Martin L, et al. Early activation of cellular stress and death pathways caused by cytoplasmic TDP-43 in the rNLS8 mouse model of ALS and FTD. Mol Psychiatry. 2023;28:2445-2461 pubmed publisher |
| Srinivasan M, Bhopale K, Caracheo A, Kaphalia L, Gong B, Popov V, et al. Exposure to binge ethanol and fatty acid ethyl esters exacerbates chronic ethanol-induced pancreatic injury in hepatic alcohol dehydrogenase-deficient deer mice. Am J Physiol Gastrointest Liver Physiol. 2022;322:G327-G345 pubmed publisher |
| Tanaka K, Kandori S, Sakka S, Nitta S, Tanuma K, Shiga M, et al. ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma. Oncol Rep. 2022;47: pubmed publisher |
| Sargeant J, Seiler D, Costain T, Madreiter Sokolowski C, Gordon D, Peden A, et al. ALG-2 and peflin regulate COPII targeting and secretion in response to calcium signaling. J Biol Chem. 2021;297:101393 pubmed publisher |
| Zhou Y, Wan X, Seidel K, Zhang M, Goodman J, Seta F, et al. Aging and Hypercholesterolemia Differentially Affect the Unfolded Protein Response in the Vasculature of ApoE-/- Mice. J Am Heart Assoc. 2021;10:e020441 pubmed publisher |
| Hong J, Park E, Lee J, Lee Y, Rooney B, Park Y. Exercise training mitigates ER stress and UCP2 deficiency-associated coronary vascular dysfunction in atherosclerosis. Sci Rep. 2021;11:15449 pubmed publisher |
| Lee S, Heo J, Jo S, Kim G, Kim S, Yoo H, et al. Progesterone receptor membrane component 1 reduces cardiac steatosis and lipotoxicity via activation of fatty acid oxidation and mitochondrial respiration. Sci Rep. 2021;11:8781 pubmed publisher |
| Luo M, Opoku E, Traughber C, Hai Q, Robinet P, Berisha S, et al. Soat1 mediates the mouse strain effects on cholesterol loading-induced endoplasmic reticulum stress and CHOP expression in macrophages. Biochim Biophys Acta Mol Cell Biol Lipids. 2021;1866:158825 pubmed publisher |
| Sophonnithiprasert T, Aruksakunwong O, Tashiro E, Kondoh Y, Muroi M, Osada H, et al. Interaction between goniothalamin and peroxisomal multifunctional enzyme type 2 triggering endoplasmic reticulum stress. Heliyon. 2020;6:e05200 pubmed publisher |
| Schneider K, Nelson G, Watson J, Morf J, Dalglish M, Luh L, et al. Protein Stability Buffers the Cost of Translation Attenuation following eIF2α Phosphorylation. Cell Rep. 2020;32:108154 pubmed publisher |
| Kataura T, Tashiro E, Nishikawa S, Shibahara K, Muraoka Y, Miura M, et al. A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers. Autophagy. 2020;:1-17 pubmed publisher |
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| Peserico D, Stranieri C, Garbin U, Mozzini C C, Danese E, Cominacini L, et al. Ezetimibe Prevents Ischemia/Reperfusion-Induced Oxidative Stress and Up-Regulates Nrf2/ARE and UPR Signaling Pathways. Antioxidants (Basel). 2020;9: pubmed publisher |
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| Manuel A, Walla M, Dorn M, Tanis R, Piroli G, Frizzell N. Fumarate and oxidative stress synergize to promote stability of C/EBP homologous protein in the adipocyte. Free Radic Biol Med. 2019;: pubmed publisher |
| Zheng M, Mitra R, Weiss E, Han Z. Rhodopsin Genomic Loci DNA Nanoparticles Improve Expression and Rescue of Retinal Degeneration in a Model for Retinitis Pigmentosa. Mol Ther. 2020;28:523-535 pubmed publisher |
| Young Baird S, Lourenço M, Elder M, Klann E, Liebau S, Dever T. Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB. Mol Cell. 2019;: pubmed publisher |
| Srinivasan M, Bhopale K, Amer S, Wan J, Kaphalia L, Ansari G, et al. Linking Dysregulated AMPK Signaling and ER Stress in Ethanol-Induced Liver Injury in Hepatic Alcohol Dehydrogenase Deficient Deer Mice. Biomolecules. 2019;9: pubmed publisher |
| Lenin R, Nagy P, Jha K, GANGARAJU R. GRP78 translocation to the cell surface and O-GlcNAcylation of VE-Cadherin contribute to ER stress-mediated endothelial permeability. Sci Rep. 2019;9:10783 pubmed publisher |
| Moskovskich A, Goldmann U, Kartnig F, Lindinger S, Konecka J, Fiume G, et al. The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection. Sci Rep. 2019;9:10471 pubmed publisher |
| Stamm C, Pasko B, Chaisavaneeyakorn S, Franco L, Nair V, Weigele B, et al. Screening Mycobacterium tuberculosis Secreted Proteins Identifies Mpt64 as a Eukaryotic Membrane-Binding Bacterial Effector. mSphere. 2019;4: pubmed publisher |
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| Cho B, Hwang J, Shin Y, Kim J, Chung T, Hyon J. Rapamycin Rescues Endoplasmic Reticulum Stress-Induced Dry Eye Syndrome in Mice. Invest Ophthalmol Vis Sci. 2019;60:1254-1264 pubmed publisher |
| Dzhashiashvili Y, Monckton C, Shah H, Kunjamma R, Popko B. The UPR-PERK pathway is not a promising therapeutic target for mutant SOD1-induced ALS. Neurobiol Dis. 2019;127:527-544 pubmed publisher |
| Blunsom N, Gomez Espinosa E, Ashlin T, Cockcroft S. Sustained phospholipase C stimulation of H9c2 cardiomyoblasts by vasopressin induces an increase in CDP-diacylglycerol synthase 1 (CDS1) through protein kinase C and cFos. Biochim Biophys Acta Mol Cell Biol Lipids. 2019;1864:1072-1082 pubmed publisher |
| Tran H, Mittal A, Sagi V, Luk K, Nguyen A, Gupta M, et al. Mast Cells Induce Blood Brain Barrier Damage in SCD by Causing Endoplasmic Reticulum Stress in the Endothelium. Front Cell Neurosci. 2019;13:56 pubmed publisher |
| Stewart A, Tan S, Clark D, Zhang H, Wong G. N-Linked Glycosylation-Dependent and -Independent Mechanisms Regulating CTRP12 Cleavage, Secretion, and Stability. Biochemistry. 2019;58:727-741 pubmed publisher |
| Searfoss G, Paisley B, Goldstein K, Baker T, Willy J. The Integrated Stress Response Regulates Cell Health of Cardiac Progenitors. Toxicol Sci. 2019;167:202-210 pubmed publisher |
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| Lenin R, Nagy P, Gentry J, GANGARAJU R. Featured Article: Deterioration of visual function mediated by senescence-associated endoplasmic reticulum stress in inflammatory tie2-TNF mice. Exp Biol Med (Maywood). 2018;243:976-984 pubmed publisher |
| Krzyzosiak A, Sigurdardottir A, Luh L, Carrara M, Das I, Schneider K, et al. Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B. Cell. 2018;174:1216-1228.e19 pubmed publisher |
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