DAPK1 Monoclonal Antibody (DAPK-55) | Invitrogen MA1-24696 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DAPK1 Monoclonal Antibody (DAPK-55)

catalog :

MA1-24696

quantity :

100 uL

price :

US 524.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DAPK-55

reactivity :

human

application :

western blot, immunoprecipitation

citations: 2

Reference
Basu A, Penumutchu S, Nguyen K, Mbonye U, Tolbert B, Karn J, et al. A Structurally Conserved RNA Element within SARS-CoV-2 ORF1a RNA and S mRNA Regulates Translation in Response to Viral S Protein-Induced Signaling in Human Lung Cells. J Virol. 2022;96:e0167821 pubmed publisher
Schmidt M, Caron N, Aly A, Lemarié F, Dal Cengio L, Ko Y, et al. DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mouse Model of Huntington Disease. Front Cell Neurosci. 2020;14:590569 pubmed publisher

product information

Product Type :

Antibody

Product Name :

DAPK1 Monoclonal Antibody (DAPK-55)

Catalog # :

MA1-24696

Quantity :

100 uL

Price :

US 524.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Non-human primate

Applications :

Immunoprecipitation: Assay-dependent, Western Blot: 1:250

Species :

Human, Non-human primate

Clone :

DAPK-55

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor. DAPK1 is involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and authophagy. It regulates both type I apoptotic and type II autophagic cell death signal, depending on the cellular setting. Type I apoptotic cell death is caspase-dependent, type II authophagic cell death is caspase-independent. DAPK1 phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. It also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.

Immunogen :

recombinant human DAP kinase expressed in bacteria

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: Assay-dependent, Western Blot: 1:250

Aliases :

D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193