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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
hnRNP C1/C2 Monoclonal Antibody (4F4)
catalog :
MA1-24631
quantity :
50 µL
price :
US 496.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4F4
reactivity :
Chinese hamsters, human
application :
western blot, ELISA, immunocytochemistry, RNA immunoprecipitation
more info or order :
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; human
Bergeron D, Pal G, Beaulieu Y, Chabot B, Bachand F. Regulated Intron Retention and Nuclear Pre-mRNA Decay Contribute to PABPN1 Autoregulation. Mol Cell Biol. 2015;35:2503-17 pubmed publisher
product information
Product Type :
Antibody
Product Name :
hnRNP C1/C2 Monoclonal Antibody (4F4)
Catalog # :
MA1-24631
Quantity :
50 µL
Price :
US 496.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Chicken, Hamster, Human, Non-human primate
Applications :
ELISA: Assay-dependent, Immunocytochemistry: 5 µg/mL, RNA Immunoprecipitation: 1.25 µg/10^6 cells, Western Blot: 0.1-0.2 µg/mL
Species :
Chicken, Hamster, Human, Non-human primate
Clone :
4F4
Isotype :
IgG1
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP C1 and C2 are encoded by one gene; the two alternatively spliced transcript variants have been described.
Immunogen :
RNP's eluted from oligo (dT) cellulose column.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunocytochemistry: 5 µg/mL, RNA Immunoprecipitation: 1.25 µg/10^6 cells, Western Blot: 0.1-0.2 µg/mL
Aliases :
AL022939; bZ1G18.4; C1; C2; D14Wsu171e; fb57h12; fi16b11; heterogeneous nuclear ribonucleoprotein C; heterogeneous nuclear ribonucleoprotein C (C1/C2); heterogeneous nuclear ribonucleoprotein C1; heterogeneous nuclear ribonucleoprotein C2; heterogeneous nuclear ribonucleoproteins C1/C2; heterogeneous nuclear ribonucleoproteins C1/C2; heterogeneous nuclear ribonucleoprotein C; heterogeneous ribonucleoprotein C1/C2; HNRNP; hnRNP C; hnRNP C protein C-terminal fragment (158 AA); hnRNP C1 / hnRNP C2; hnRNP C1/C2; hnRNP C2; hnRNP core protein C; HNRNPC; hnrnp-C; hnRNPC1; hnRNPC2; HNRPC; Hnrpc1; Hnrpc2; hypothetical protein LOC406352; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; snoRNA MBI-122; SNRPC; wu:fb57h12; wu:fi16b11; zgc:55701
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA