HEC1 Monoclonal Antibody (9G3.23) | Invitrogen MA1-23308 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HEC1 Monoclonal Antibody (9G3.23)

catalog :

MA1-23308

quantity :

100 µL

price :

US 496.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9G3.23

reactivity :

Chinese hamsters, human, mouse, pigs

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, proximity ligation assay

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:100	Bodor D, Mata J, Sergeev M, David A, Salimian K, Panchenko T, et al. The quantitative architecture of centromeric chromatin. elife. 2014;3:e02137 pubmed publisher
	Shrestha R, Rossi A, Wangsa D, Hogan A, Zaldana K, Suva E, et al. CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity. J Cell Biol. 2021;220: pubmed publisher
	Murillo Pineda M, Valente L, Dumont M, Mata J, Fachinetti D, Jansen L. Induction of spontaneous human neocentromere formation and long-term maturation. J Cell Biol. 2021;220: pubmed publisher
	Herman J, Miller M, Biggins S. chTOG is a conserved mitotic error correction factor. elife. 2020;9: pubmed publisher
	Milagre I, Pereira C, Oliveira R, Jansen L. Reprogramming of human cells to pluripotency induces CENP-A chromatin depletion. Open Biol. 2020;10:200227 pubmed publisher
	Kuijt T, Lambers M, Weterings S, Ponsioen B, Bolhaqueiro A, Staijen D, et al. A Biosensor for the Mitotic Kinase MPS1 Reveals Spatiotemporal Activity Dynamics and Regulation. Curr Biol. 2020;30:3862-3870.e6 pubmed publisher
	Mitra S, Bodor D, David A, Abdul Zani I, Mata J, Neumann B, et al. Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin. Nat Commun. 2020;11:501 pubmed publisher
	Lee M, Lin L, Equilibrina I, Uchiyama S, Matsunaga S, Fukui K. ASURA (PHB2) Is Required for Kinetochore Assembly and Subsequent Chromosome Congression. Acta Histochem Cytochem. 2011;44:247-58 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HEC1 Monoclonal Antibody (9G3.23)

Catalog # :

MA1-23308

Quantity :

100 µL

Price :

US 496.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Hamster, Human, Mouse, Non-human primate, Porcine, Rodent

Applications :

Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: 1-5 µg/mL, Proximity Ligation Assay (PLA): Assay-dependent, Western Blot: 1:500-1:3,000

Species :

Hamster, Human, Mouse, Non-human primate, Porcine, Rodent

Clone :

9G3.23

Isotype :

IgG2a

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Hec1 is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.

Immunogen :

Partial human HEC1 protein consisting of amino acids 56-642.

Format :

Liquid

Applications w/Dilutions :

Aliases :

2610020P18Rik; AV139730; HEC; HEC1; HEC-1; HEC2; HEC4; Highly expressed in cancer protein; highly expressed in cancer, rich in leucine heptad repeats; HsHec1; hsNDC80; kinetochore associated 2; kinetochore protein Hec1; Kinetochore protein NDC80 homolog; kinetochore-associated protein 2; KNTC2; NDC80; NDC80 homolog, kinetochore complex component; NDC80 homolog, kinetochore complex component (S. cerevisiae); NDC80 kinetochore complex component; NDC80 kinetochore complex component homolog; NDC80, kinetochore complex component; putative kinetochore protein NDC80 like protein; retinoblastoma-associated protein HEC; TID3

more info or order :

Invitrogen product webpage