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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TSG101 Monoclonal Antibody (4A10)
catalog :
MA1-23296
quantity :
100 µL
price :
US 496.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4A10
reactivity :
Chinese hamsters, human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 25
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig 1a
Stefanius K, Servage K, de Souza Santos M, Gray H, Toombs J, Chimalapati S, et al. Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation. elife. 2019;8: pubmed publisher
Elsayed R, Elashiry M, Tran C, Yang T, Carroll A, Liu Y, et al. Engineered Human Dendritic Cell Exosomes as Effective Delivery System for Immune Modulation. Int J Mol Sci. 2023;24: pubmed publisher
Taymans J, Mutez E, Sibran W, Vandewynckel L, Deldycke C, Bleuse S, et al. Alterations in the LRRK2-Rab pathway in urinary extracellular vesicles as Parkinson's disease and pharmacodynamic biomarkers. NPJ Parkinsons Dis. 2023;9:21 pubmed publisher
Hu L, Wang B, Fan Y, He Z, Zheng W. Exosomal miR-23b from bone marrow mesenchymal stem cells alleviates oxidative stress and pyroptosis after intracerebral hemorrhage. Neural Regen Res. 2023;18:560-567 pubmed publisher
Zhu Z, Jia F, Ahmed W, Zhang G, Wang H, Lin C, et al. Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke. Neural Regen Res. 2023;18:404-409 pubmed publisher
Bordin A, Chiriv xec M, Pagano F, Milan M, Iuliano M, Scaccia E, et al. Human platelet lysate-derived extracellular vesicles enhance angiogenesis through miR-126. Cell Prolif. 2022;55:e13312 pubmed publisher
Mayoral J, Guevara R, Rivera Cuevas Y, Tu V, Tomita T, Romano J, et al. Dense Granule Protein GRA64 Interacts with Host Cell ESCRT Proteins during Toxoplasma gondii Infection. MBio. 2022;:e0144222 pubmed publisher
Xia W, Lu Z, Chen W, Zhou J, Zhao Y. Excess fatty acids induce pancreatic acinar cell pyroptosis through macrophage M1 polarization. BMC Gastroenterol. 2022;22:72 pubmed publisher
Xuan Z, Chen C, Tang W, Ye S, Zheng J, Zhao Y, et al. TKI-Resistant Renal Cancer Secretes Low-Level Exosomal miR-549a to Induce Vascular Permeability and Angiogenesis to Promote Tumor Metastasis. Front Cell Dev Biol. 2021;9:689947 pubmed publisher
Elsayed R, Elashiry M, Liu Y, El Awady A, Hamrick M, Cutler C. Porphyromonas gingivalis Provokes Exosome Secretion and Paracrine Immune Senescence in Bystander Dendritic Cells. Front Cell Infect Microbiol. 2021;11:669989 pubmed publisher
Shpigelman J, Lao F, Yao S, Li C, Saito T, Sato Kaneko F, et al. Generation and Application of a Reporter Cell Line for the Quantitative Screen of Extracellular Vesicle Release. Front Pharmacol. 2021;12:668609 pubmed publisher
Fong M, Yan W, Ghassemian M, Wu X, Zhou X, Cao M, et al. Cancer-secreted miRNAs regulate amino-acid-induced mTORC1 signaling and fibroblast protein synthesis. EMBO Rep. 2021;22:e51239 pubmed publisher
Palviainen M, Laukkanen K, Tavukcuoglu Z, Velagapudi V, Kärkkäinen O, Hanhineva K, et al. Cancer Alters the Metabolic Fingerprint of Extracellular Vesicles. Cancers (Basel). 2020;12: pubmed publisher
Augimeri G, La Camera G, Gelsomino L, Giordano C, Panza S, Sisci D, et al. Evidence for Enhanced Exosome Production in Aromatase Inhibitor-Resistant Breast Cancer Cells. Int J Mol Sci. 2020;21: pubmed publisher
Kwon Y, Nukala S, Srivastava S, Miyamoto H, Ismail N, Rehman J, et al. Detection of Viral RNA Fragments in Human iPSC-Cardiomyocytes following Treatment with Extracellular Vesicles from SARS-CoV-2 Coding-Sequence-Overexpressing Lung Epithelial Cells. bioRxiv. 2020;: pubmed publisher
Dinh P, Paudel D, Brochu H, Popowski K, Gracieux M, Cores J, et al. Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis. Nat Commun. 2020;11:1064 pubmed publisher
Laukkanen K, Saarinen M, Mallet F, Aatonen M, Hau A, Ranki A. Cutaneous T-Cell Lymphoma (CTCL) Cell Line-Derived Extracellular Vesicles Contain HERV-W-Encoded Fusogenic Syncytin-1. J Invest Dermatol. 2020;140:1466-1469.e4 pubmed publisher
Venturini A, Passalacqua M, Pelassa S, Pastorino F, Tedesco M, Cortese K, et al. Exosomes From Astrocyte Processes: Signaling to Neurons. Front Pharmacol. 2019;10:1452 pubmed publisher
Ñahui Palomino R, Vanpouille C, Laghi L, Parolin C, Melikov K, Backlund P, et al. Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues. Nat Commun. 2019;10:5656 pubmed publisher
Trubetckaia O, Lane A, Qian L, Zhou P, Lane D. Alpha-synuclein is strategically positioned for afferent modulation of midbrain dopamine neurons and is essential for cocaine preference. Commun Biol. 2019;2:418 pubmed publisher
Wen S, Dooner M, Papa E, Del Tatto M, Pereira M, Borgovan T, et al. Biodistribution of Mesenchymal Stem Cell-Derived Extracellular Vesicles in a Radiation Injury Bone Marrow Murine Model. Int J Mol Sci. 2019;20: pubmed publisher
Zhang L, Liu H, Xu K, Ling Z, Huang Y, Hu Q, et al. Hypoxia preconditioned renal tubular epithelial cell-derived extracellular vesicles alleviate renal ischaemia-reperfusion injury mediated by the HIF-1α/Rab22 pathway and potentially affected by microRNAs. Int J Biol Sci. 2019;15:1161-1176 pubmed publisher
Mondal A, Ashiq K, Phulpagar P, Singh D, Shiras A. Effective Visualization and Easy Tracking of Extracellular Vesicles in Glioma Cells. Biol Proced Online. 2019;21:4 pubmed publisher
Chin A, Yan W, Cao M, Liu X, Wang S. Polarized Secretion of Extracellular Vesicles by Mammary Epithelia. J Mammary Gland Biol Neoplasia. 2018;23:165-176 pubmed publisher
Sharma S, Arunachalam P, Menon M, Ragupathy V, Satya R, Jebaraj J, et al. PTAP motif duplication in the p6 Gag protein confers a replication advantage on HIV-1 subtype C. J Biol Chem. 2018;293:11687-11708 pubmed publisher
product information
Product Type :
Antibody
Product Name :
TSG101 Monoclonal Antibody (4A10)
Catalog # :
MA1-23296
Quantity :
100 µL
Price :
US 496.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Hamster, Human, Mouse, Non-human primate, Rat
Applications :
ELISA: Assay-dependent, Flow Cytometry: 1:25-1:200, Immunocytochemistry: 1:500-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunomicroscopy: 1:10, Immunoprecipitation: Assay-dependent, Western Blot: 1:500-1:3,000
Species :
Hamster, Human, Mouse, Non-human primate, Rat
Clone :
4A10
Isotype :
IgG1
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
TSG101-4A10 recognizes TSG101 protein, the product of a recently identified Tumor Susceptibility Gene whose inactivation in mouse fibroblasts results in cell transformation and the ability of those cells to form tumors in nude mice. The TSG101 gene encodes a 46 kDa protein and contains a proline-rich domain and a leucine-zipper motif within a coiled-coil domain near the carboxyl terminus.
Immunogen :
Residues 167-374 of TSG101, expressed in E. coli.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Flow Cytometry: 1:25-1:200, Immunocytochemistry: 1:500-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunomicroscopy: 1:10, Immunoprecipitation: Assay-dependent, Western Blot: 1:500-1:3,000
Aliases :
AI255943; CC2; ESCRTI complex subunit TSG101; ESCRT-I complex subunit TSG101; Rw; TSG 101; TSG10; TSG101; Tumor supressor; tumor susceptibility 101; tumor susceptibility gene 10; tumor susceptibility gene 101; tumor susceptibility gene 101 protein; tumor susceptibility protein; VPS23
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA