RbAp46/RbAp48 Monoclonal Antibody (15G12) | Invitrogen MA1-23277 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RbAp46/RbAp48 Monoclonal Antibody (15G12)

catalog :

MA1-23277

quantity :

100 µL

price :

US 460.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

15G12

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, RNA immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
RNA immunoprecipitation; human; fig 3	Holdt L, Hoffmann S, Sass K, Langenberger D, Scholz M, Krohn K, et al. Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks. PLoS Genet. 2013;9:e1003588 pubmed publisher
	Qian Y, Lee E. Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast. J Biol Chem. 1995;270:25507-13 pubmed

product information

Product Type :

Antibody

Product Name :

RbAp46/RbAp48 Monoclonal Antibody (15G12)

Catalog # :

MA1-23277

Quantity :

100 µL

Price :

US 460.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunoprecipitation: 0.2-1 µg/mL, Western Blot: 1:500-1:3,000

Species :

Human, Mouse

Clone :

15G12

Isotype :

IgG2a

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

RbAp48-15G12 recognizes full length RbAp48 (48 kDa) and RbAp46 (46 kDa), related nuclear proteins first isolated by their ability to interact with the carboxyl-terminus of the retinoblastoma protein (Rb). These two proteins are highly homologous at the amino acid level and are related functionally to members of the WD (Trp-Asp) repeat family of proteins. RbAp48 is one of the three subunits of CAF-1, can bind to histone H4 and is a subunit of human histone deacetylase HD1. Both RbAp48 and RbAp46 interact with HDAC1 and mSin3 in vivo.

Immunogen :

The complete coding region (amino acids 1-425) of RbAp48 expressed in E. coli.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunoprecipitation: 0.2-1 µg/mL, Western Blot: 1:500-1:3,000

Aliases :

AA409861; AI173248; AU019541; BB114024; CAF-1 p48 subunit; CAF-1 subunit C; CAF-I 48 kDa subunit; CAF-I p48; chromatin assembly factor 1 subunit C; Chromatin assembly factor I p48 subunit; chromatin assembly factor/CAF-1 p48 subunit; G1/S transition control protein-binding protein; G1/S transition control protein-binding protein RbAp46; histone acetyltransferase type B subunit 2; Histone-binding protein RBBP4; histone-binding protein RBBP7; lin-53; mRbAp46; mRbAp48; MSI1 protein homolog; nucleosome-remodeling factor subunit RBAP46; Nucleosome-remodeling factor subunit RBAP48; NURF55; RB binding protein 4, chromatin remodeling factor; RB binding protein 7, chromatin remodeling factor; Rbap46; RBAP48; Rbbp4; RBBP-4; RBBP7; RBBP-7; retinoblastoma binding protein 4; retinoblastoma binding protein 7; retinoblastoma-binding protein 4; Retinoblastoma-binding protein 7; retinoblastoma-binding protein p46; Retinoblastoma-binding protein p48; retinoblastoma-binding protein RbAp46

more info or order :

Invitrogen product webpage