RAD50 Monoclonal Antibody (13B3) | Invitrogen MA1-23269 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RAD50 Monoclonal Antibody (13B3)

catalog :

MA1-23269

quantity :

100 µL

price :

US 496.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13B3

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse western blot; mouse	Soutoglou E, Dorn J, Sengupta K, Jasin M, Nussenzweig A, Ried T, et al. Positional stability of single double-strand breaks in mammalian cells. Nat Cell Biol. 2007;9:675-82 pubmed
	Sun Y, Ning X, Fan J, Hu J, Jiang Y, Hu Z, et al. Loss of tumor suppressor inositol polyphosphate 4-phosphatase type B impairs DNA double-strand break repair by destabilization of DNA tethering protein Rad50. Cell Death Dis. 2020;11:292 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RAD50 Monoclonal Antibody (13B3)

Catalog # :

MA1-23269

Quantity :

100 µL

Price :

US 496.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunoprecipitation: Assay-dependent, In vitro Assay: Assay-dependent, Western Blot: 1:500-1:3,000

Species :

Human, Mouse, Non-human primate, Rat

Clone :

13B3

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Rad50-13B3 recognizes human Rad50, a 153a protein involved in DNA double strand break repair. Rad50 is associated with Mre11 and p95 (Nibrin) to form a multiprotein complex involved in the double strand break repair process. Upon DNA damage, Rad50 and Mre11 redistribute and are co-localized within the nucleus of damaged cells.

Immunogen :

Amino acids 1-425 of Rad50 expressed in E. coli.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunoprecipitation: Assay-dependent, In vitro Assay: Assay-dependent, Western Blot: 1:500-1:3,000

Aliases :

153 kDa protein; DNA repair protein RAD50; hRad50; hsRAD50; I79_004319; mRad50; Mrell; MRX complex DNA-binding subunit; N0872; NBSLD; Rad50; RAD50 2; RAD50 double strand break repair protein; RAD50 homolog (S. cerevisiae); RAD50 homolog, double strand break repair protein; RAD50 PEN; RAD502; RAD50-2; RAD50-3; Rad50l; YNL250W

more info or order :

Invitrogen product webpage