JAB1 Monoclonal Antibody (2A10) | Invitrogen MA1-23244 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

JAB1 Monoclonal Antibody (2A10)

catalog :

MA1-23244

quantity :

100 µL

price :

US 456.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2A10

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; loading ...; fig 3b	Chen H, Padia R, Li T, Li Y, Li B, Jin L, et al. Signaling of MK2 sustains robust AP1 activity for triple negative breast cancer tumorigenesis through direct phosphorylation of JAB1. NPJ Breast Cancer. 2021;7:91 pubmed publisher

product information

Product Type :

Antibody

Product Name :

JAB1 Monoclonal Antibody (2A10)

Catalog # :

MA1-23244

Quantity :

100 µL

Price :

US 456.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Drosophila, Human, Mouse, Rat

Applications :

Immunocytochemistry: 5 µg/ml, Immunohistochemistry: Assay-dependent, Immunoprecipitation: 0.5-1 µg/mL, Western Blot: 1:500-1:3,000

Species :

Drosophila, Human, Mouse, Rat

Clone :

2A10

Isotype :

IgG2b

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the "Signalosome", which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.

Immunogen :

The full-length mouse JAB-1 gene expressed in E. coli.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5 µg/ml, Immunohistochemistry: Assay-dependent, Immunoprecipitation: 0.5-1 µg/mL, Western Blot: 1:500-1:3,000

Aliases :

38 kDa Mov34 homolog; AI303502; COP9 (constitutive photomorphogenic) homolog, subunit 5; COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana); COP9 complex S5; COP9 constitutive photomorphogenic homolog subunit 5; COP9 signalosome complex subunit 5; COP9 signalosome subunit 5; Cops5; CSN5; JAB1; Jun activation domain-binding protein 1; Jun coactivator; Kic2; Kip1 C-terminus-interacting protein 2; MGC3149; Mov34; MOV-34; SGN5; signalosome subunit 5; testis secretory sperm-binding protein Li 231m

more info or order :

Invitrogen product webpage