FEN1 Monoclonal Antibody (4E7) | Invitrogen MA1-23228 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FEN1 Monoclonal Antibody (4E7)

catalog :

MA1-23228

quantity :

100 uL

price :

US 464.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4.00E+07

The same clone is also sold as:

Novus Biologicals: NB100-150

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 1

Reference
Vaitsiankova A, Burdova K, Sobol M, Gautam A, Benada O, Hanzlikova H, et al. PARP inhibition impedes the maturation of nascent DNA strands during DNA replication. Nat Struct Mol Biol. 2022;29:329-338 pubmed publisher

product information

Product Type :

Antibody

Product Name :

FEN1 Monoclonal Antibody (4E7)

Catalog # :

MA1-23228

Quantity :

100 uL

Price :

US 464.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:500-1:3,000

Species :

Human, Mouse

Clone :

4.00E+07

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 a protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems.

Immunogen :

Recombinant human FEN-1 protein encoding amino acids 1-380 purified E. coli.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:500-1:3,000

Aliases :

AW538437; DNase IV; fen1; FEN-1; fen1 {ECO:0000255; FEN-1 {ECO:0000255; Flap endonuclease 1; flap endonuclease 1 {ECO:0000255; flap structure specific endonuclease 1; flap structure-specific endonuclease 1; flap structure-specific endonuclease 1 {ECO:0000255; HAMAP-Rule:MF_03140}; hFEN-1; Maturation factor 1; maturation factor-1; MF1; RAD2