GUCY1B2 (soluble) Monoclonal Antibody (GC25) | Invitrogen MA1-23047 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GUCY1B2 (soluble) Monoclonal Antibody (GC25)

catalog :

MA1-23047

quantity :

200 ug

price :

US 480.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GC25

application :

western blot, ELISA, immunohistochemistry

product information

Product Type :

Antibody

Product Name :

GUCY1B2 (soluble) Monoclonal Antibody (GC25)

Catalog # :

MA1-23047

Quantity :

200 ug

Price :

US 480.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Immunohistochemistry: Assay-Dependent, Western Blot: Assay-dependent

Species :

Human

Clone :

GC25

Isotype :

IgG2a

Storage :

4 C, do not freeze

Description :

Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one 72 kDa alpha subunit and one 65 kDa beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme.

Immunogen :

Recombinant full length protein: human soluble guanylate cyclase alpha1 beta1 heterodimer.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunohistochemistry: Assay-Dependent, Western Blot: Assay-dependent

Aliases :

B930025B03; GCS beta2; GC-SB2; GCS-beta2; GCS-beta-2; guanylate cyclase 1 soluble subunit beta 2 (pseudogene); guanylate cyclase 1, soluble, beta 2; Guanylate cyclase soluble beta 2 (GTP pyrophosphate - lyase); guanylate cyclase soluble subunit beta-2; Guanylate cyclase, soluble, beta 2 (GTP pyrophosphate - lyase); Gucy1b2; Gucy1b2a; Gucy1b2b; SGC; soluble guanylate cyclase beta 2a; soluble guanylate cyclase beta 2b; soluble guanylyl cyclase beta2 subunit