Bacillus anthracis Lethal Factor Monoclonal Antibody (BAL0106) | Invitrogen MA1-22669 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Bacillus anthracis Lethal Factor Monoclonal Antibody (BAL0106)

catalog :

MA1-22669

quantity :

100 ug

price :

US 480.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

BAL0106

product information

Product Type :

Antibody

Product Name :

Bacillus anthracis Lethal Factor Monoclonal Antibody (BAL0106)

Catalog # :

MA1-22669

Quantity :

100 ug

Price :

US 480.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Bacteria

Applications :

ELISA: Assay-dependent

Species :

Bacteria

Clone :

BAL0106

Isotype :

IgG1

Storage :

4 C, do not freeze

Description :

Anthrax toxin is a three-protein exotoxin secreted by virulent strains of the bacterium Bacillus anthracis, the causative agent of anthrax. Anthrax toxin is composed of a cell-binding protein, known as protective antigen (PA), and two enzyme components, called edema factor (EF) and lethal factor (LF). These three protein components act together to impart their physiological effects. Assembled complexes containing the toxin components are endocytosed. In the endosome, the enzymatic components of the toxin translocate into the cytoplasm of a target cell. Once in the cytosol, the enzymatic components of the toxin disrupts various immune cell functions, namely cellular signaling and cell migration. The toxin may even induce cell lysis, as is observed for macrophage cells. Anthrax toxin allows the bacteria to evade the immune system, proliferate, and ultimately kill the host animal. Research on anthrax toxin also provides insight into the generation of macromolecular assemblies, and on protein translocation, pore formation, endocytosis, and other biochemical processes.

Immunogen :

Highly purified lethal factor antigen of Bacillus anthracis.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent

Aliases :

Anthrax LF; B. anthracis LF