IL-6 Monoclonal Antibody (MP5-20F3) | Invitrogen MA1-22531 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-6 Monoclonal Antibody (MP5-20F3)

catalog :

MA1-22531

quantity :

50µg

price :

US 349.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

MP5-20F3

reactivity :

human, mouse

application :

immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, blocking or activating experiments

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 2	Saha A, O Connor R, Thangavelu G, Lovitch S, Dandamudi D, Wilson C, et al. Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality. J Clin Invest. 2016;126:2642-60 pubmed publisher
ELISA; mouse; fig 5a	Raynor J, Karns R, Almanan M, Li K, Divanovic S, Chougnet C, et al. IL-6 and ICOS Antagonize Bim and Promote Regulatory T Cell Accrual with Age. J Immunol. 2015;195:944-52 pubmed publisher
ELISA; mouse	Matsumoto S, Hara T, Nagaoka M, Mike A, Mitsuyama K, Sako T, et al. A component of polysaccharide peptidoglycan complex on Lactobacillus induced an improvement of murine model of inflammatory bowel disease and colitis-associated cancer. Immunology. 2009;128:e170-80 pubmed publisher
ELISA; human; 1.5 ug/ml	Loewenbrueck K, Tigno Aranjuez J, Boehm B, Lehmann P, Tary Lehmann M. Th1 responses to beta-amyloid in young humans convert to regulatory IL-10 responses in Down syndrome and Alzheimer's disease. Neurobiol Aging. 2010;31:1732-42 pubmed publisher
blocking or activating experiments; mouse; 1.25 ug/ml	Martín Orozco E, Kobayashi H, Van Uden J, Nguyen M, Kornbluth R, Raz E. Enhancement of antigen-presenting cell surface molecules involved in cognate interactions by immunostimulatory DNA sequences. Int Immunol. 1999;11:1111-8 pubmed
	Pangrazzi L, Meryk A, Naismith E, Koziel R, Lair J, Krismer M, et al. "Inflamm-aging" influences immune cell survival factors in human bone marrow. Eur J Immunol. 2017;47:481-492 pubmed publisher
	Monner D, Denker B. Characterization of clonally derived, spontaneously transformed bone marrow macrophage cell lines from lipopolysaccharide hyporesponsive LPS(d) and normal LPS(n) mice. J Leukoc Biol. 1997;61:469-80 pubmed

product information

Product Type :

Antibody

Product Name :

IL-6 Monoclonal Antibody (MP5-20F3)

Catalog # :

MA1-22531

Quantity :

50µg

Price :

US 349.00

Clonality :

Monoclonal

Purity :

IgG fraction

Host :

Rat

Reactivity :

Mouse

Applications :

ELISA: 1-4 µg/ml, Immunocytochemistry: Assay-dependent, Immunofluorescence: Assay dependent, Immunoprecipitation: Assay dependent, Inhibition Assays: Assay dependent, Neutralization: Assay-dependent

Species :

Mouse

Clone :

MP5-20F3

Isotype :

IgG1

Storage :

4° C, do not freeze

Description :

Interleukin 6 (IL-6) is a pluripotent 20-22 kDa cytokine that plays a role in the pathophysiology of severe infection and regulates the immune response, acute phase reaction and hematopoiesis. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. Continuous IL-6 gene expression makes an essential contribution to a multi-step oncogenesis of plasma cell neoplasia. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas.

Immunogen :

Interleukin 6 (IL-6)

Format :

Liquid

Applications w/Dilutions :

ELISA: 1-4 µg/ml, Immunocytochemistry: Assay-dependent, Immunofluorescence: Assay dependent, Immunoprecipitation: Assay dependent, Inhibition Assays: Assay dependent, Neutralization: Assay-dependent

Aliases :

Interleukin-6, BSF2, HGF, HSF, IFNB2, IL-6, B-cell stimulatory factor 2, BSF-2, Interferon beta-2, Hybridoma growth factor, CTL differentiation factor