E-selectin Monoclonal Antibody (1.2B6) | Invitrogen MA1-22165 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

E-selectin Monoclonal Antibody (1.2B6)

catalog :

MA1-22165

quantity :

100 µg

price :

US 475

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1.2B6

reactivity :

human, pigs

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, other

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
other; human; loading ...; fig 2b	BÃ¦k R, SÃ¸ndergaard E, Varming K, JÃ¸rgensen M. The impact of various preanalytical treatments on the phenotype of small extracellular vesicles in blood analyzed by protein microarray. J Immunol Methods. 2016;438:11-20 pubmed publisher
ELISA; human; fig 2	JÃ¸rgensen M, BÃ¦k R, Varming K. Potentials and capabilities of the Extracellular Vesicle (EV) Array. J Extracell Vesicles. 2015;4:26048 pubmed publisher
immunocytochemistry; human	Huegel R, Velasco P, De La Luz Sierra M, Christophers E, Schröder J, Schwarz T, et al. Novel anti-inflammatory properties of the angiogenesis inhibitor vasostatin. J Invest Dermatol. 2007;127:65-74 pubmed
	Ku C, Zerboni L, Ito H, Graham B, Wallace M, Arvin A. Varicella-zoster virus transfer to skin by T Cells and modulation of viral replication by epidermal cell interferon-alpha. J Exp Med. 2004;200:917-25 pubmed

product information

Product Type :

Antibody

Product Name :

E-selectin Monoclonal Antibody (1.2B6)

Catalog # :

MA1-22165

Quantity :

100 µg

Pricing :

US 475

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Porcine

Applications :

ELISA: 10 µg/mL, Flow Cytometry: 10 µg/mL, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): 1-10 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Human, Porcine

Clone :

1.2B6

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Leukocytes adhere to the blood vessel endothelium during extravasation in postcapillary venules of lymph nodes. In addition, leukocyte adhesion occurs in the capillaries and small venules at any site in the body after onset of inflammation. This response is immediate and involves a cascade of adhesion receptors. At the endothelial surface members of the selectin and immunoglobulin superfamilies participate in this cascade. Selectins are C-type cell surface lectins that play a role in leukocyte adhesion to the blood vessel wall endothelium. E-selectin (CD62E) is an endothelial cell specific selectin that is expressed only after activation with proinflammatory cytokines. In vitro experiments have shown that IL-1, TNFalpha and bacterial wall components like lipopolysaccharides induce the transcription of E-selectin in a NFkB dependent signaling cascade. E-selectin has been associated with blood vessel endothelium in diverse inflammatory situations.

Immunogen :

Human E-Selectin (ELAM-1)

Format :

Liquid

Applications w/Dilutions :

ELISA: 10 µg/mL, Flow Cytometry: 10 µg/mL, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): 1-10 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

CD62 antigen-like family member E; CD62E; e selectin; Elam; ELAM1; ELAM-1; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule; endothelial leukocyte adhesion molecule 1; endothelial leukocyte adhesion molecule I; ESEL; E-selectin; LECAM2; leukocyte endothelial cell adhesion molecule 2; leukocyte-endothelial cell adhesion molecule 2; RP1-117P20.2; SELE; selectin E; selectin E (endothelial adhesion molecule 1); selectin, endothelial cell

more info or order :

Invitrogen product webpage