Desmin Monoclonal Antibody (DE-U-10) | Invitrogen MA1-22150 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Desmin Monoclonal Antibody (DE-U-10)

catalog :

MA1-22150

quantity :

100 µL

price :

US 450.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DE-U-10

reactivity :

domestic goat, Chinese hamsters, human, mouse, rat, bovine, pigs , cat, domestic sheep, domestic rabbit

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; rat immunocytochemistry; human	Steiner Champliaud M, Schneider Y, Favre B, Paulhe F, Praetzel Wunder S, Faulkner G, et al. BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin. Exp Cell Res. 2010;316:297-313 pubmed publisher
	Moneo Corcuera D, Viedma Poyatos x, Stamatakis K, P xe9 rez Sala D. Desmin Reorganization by Stimuli Inducing Oxidative Stress and Electrophiles: Role of Its Single Cysteine Residue. Antioxidants (Basel). 2023;12: pubmed publisher
	Bernasconi P, Carboni N, Ricci G, Siciliano G, Politano L, Maggi L, et al. Elevated TGF β2 serum levels in Emery-Dreifuss Muscular Dystrophy: Implications for myocyte and tenocyte differentiation and fibrogenic processes. Nucleus. 2018;9:292-304 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Desmin Monoclonal Antibody (DE-U-10)

Catalog # :

MA1-22150

Quantity :

100 µL

Price :

US 450.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Bovine, Feline, Goat, Hamster, Human, Many, Mouse, Ovine, Porcine, Rabbit, Rat

Applications :

Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): 1:20-1:40, Western Blot: 1:200

Species :

Bovine, Feline, Goat, Hamster, Human, Many, Mouse, Ovine, Porcine, Rabbit, Rat

Clone :

DE-U-10

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Desmin (approximately 53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue, i.e. rhabdomyosarcomas and leiomyosarcomas. Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed.

Immunogen :

Purified, full length, native, pig desmin protein.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): 1:20-1:40, Western Blot: 1:200

Aliases :

CMD1I; CSM1; CSM2; DES; Desmin; desmin-like protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793; I79_018932; intermediate filament protein; LGMD2R; MFM1; muscle-specific intermediate filament desmin; muscle-specific intermediate filament protein; mutant desmin p.K241E; SCPNK; similar to desmin

more info or order :

Invitrogen product webpage