This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IGF1R alpha Monoclonal Antibody (1H7)
catalog :
MA1-21540
quantity :
50 ug
price :
US 474.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1H7

The same clone is also sold as:
reactivity :
human
application :
western blot, immunocytochemistry, neutralization
citations: 1
Reference
Su W, Chou H, Chang C, Lee Y, Chen W, Huang K, et al. Differential activation of a C/EBP beta isoform by a novel redox switch may confer the lipopolysaccharide-inducible expression of interleukin-6 gene. J Biol Chem. 2003;278:51150-8 pubmed
product information
Product Type :
Antibody
Product Name :
IGF1R alpha Monoclonal Antibody (1H7)
Catalog # :
MA1-21540
Quantity :
50 ug
Price :
US 474.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human
Applications :
Functional Assay: Assay-dependent, Immunocytochemistry: 1:100, Neutralization: Assay-dependent, Western Blot: Assay-dependent
Species :
Human
Clone :
1H7
Isotype :
IgG1
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
IGF1R (Insulin-like Growth Factor1 Receptor) is a receptor tyrosine kinase that mediates actions of insulin-like growth factor 1 (IFG1). It binds IGF1 with high affinity and IGF2/insulin with lower affinity. Activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survial of malignant cells. Ligand binding activates the receptor kinase and leads to receptor autophosphorylation and tyrosines phosphorylation of multiple substrates that function as signaling adapter proteins.
Immunogen :
Purified human placental IGF-1 receptors
Format :
Liquid
Applications w/Dilutions :
Functional Assay: Assay-dependent, Immunocytochemistry: 1:100, Neutralization: Assay-dependent, Western Blot: Assay-dependent
Aliases :
A330103N21Rik; CD221; D930020L01; hyft; IGF-1 receptor; Igf1r; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA