CENPA Monoclonal Antibody (3-19) | Invitrogen MA1-20832 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CENPA Monoclonal Antibody (3-19)

catalog :

MA1-20832

quantity :

50 ug

price :

US 524.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

19-Mar

reactivity :

human, chicken

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section

citations: 11

Reference
Valles S, Godek K, Compton D. Cyclin A/Cdk1 promotes chromosome alignment and timely mitotic progression. bioRxiv. 2023;: pubmed publisher
Landeros A, Wallace D, Rahi A, Magdongon C, Suraneni P, Amin M, et al. Nuclear lamin A-associated proteins are required for centromere assembly. bioRxiv. 2023;: pubmed publisher
Smurova K, Damizia M, Irene C, Stancari S, Berto G, Perticari G, et al. Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores. Nat Commun. 2023;14:3172 pubmed publisher
Shrestha R, Balachandra V, Kim J, Rossi A, Vadlamani P, Sethi S, et al. The histone H3/H4 chaperone CHAF1B prevents the mislocalization of CENP-A for chromosomal stability. J Cell Sci. 2023;136: pubmed publisher
Rodrigues A, MacQuarrie K, Freeman E, Lin A, Willis A, Xu Z, et al. Nucleoli and the nucleoli-centromere association are dynamic during normal development and in cancer. Mol Biol Cell. 2023;34:br5 pubmed publisher
Bleiler M, Cyr A, Wright D, Giardina C. Incorporation of 53BP1 into phase-separated bodies in cancer cells during aberrant mitosis. J Cell Sci. 2023;136: pubmed publisher
Zhong X, Yu X, Chang H. Exploration of a Novel Prognostic Nomogram and Diagnostic Biomarkers Based on the Activity Variations of Hallmark Gene Sets in Hepatocellular Carcinoma. Front Oncol. 2022;12:830362 pubmed publisher
Tsevegjav B, Takano A, Zhu M, Yoshitake Y, Shinohara M, Daigo Y. Holliday junction recognition protein as a prognostic biomarker and therapeutic target for oral cancer. Int J Oncol. 2022;60: pubmed publisher
Zasadzińska E, Huang J, Bailey A, Guo L, Lee N, Srivastava S, et al. Inheritance of CENP-A Nucleosomes during DNA Replication Requires HJURP. Dev Cell. 2018;47:348-362.e7 pubmed publisher
Wynne D, Funabiki H. Heterogeneous architecture of vertebrate kinetochores revealed by three-dimensional superresolution fluorescence microscopy. Mol Biol Cell. 2016;27:3395-3404 pubmed
Minocherhomji S, Ying S, Bjerregaard V, Bursomanno S, Aleliunaite A, Wu W, et al. Replication stress activates DNA repair synthesis in mitosis. Nature. 2015;528:286-90 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CENPA Monoclonal Antibody (3-19)

Catalog # :

MA1-20832

Quantity :

50 ug

Price :

US 524.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Chicken, Human

Applications :

Immunocytochemistry: 10 ug/mL, Immunohistochemistry (Paraffin): 5 ug/mL, Neutralization: Assay-dependent, Western Blot: 1 ug/mL

Species :

Chicken, Human

Clone :

19-Mar

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.

Immunogen :

Synthetic peptide corresponding to residues P(3) R R R S R K P E A P R R R S P S(19) of human CENPA protein.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 10 ug/mL, Immunohistochemistry (Paraffin): 5 ug/mL, Neutralization: Assay-dependent, Western Blot: 1 ug/mL

Aliases :

CenH3; CENP A; CENPA; CENP-A; Centromere autoantigen A; centromere protein A; centromere protein A, 17kDa; centromere-specific histone; ggCENP-A; histone H3-like centromeric protein A; RGD1563607