RACGAP1 Monoclonal Antibody (23A8) | Invitrogen MA1-20580 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RACGAP1 Monoclonal Antibody (23A8)

catalog :

MA1-20580

quantity :

50 ug

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

23A8

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section, blocking or activating experiments

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 3g	Li X, He L, Luo J, Zheng Y, Zhou Y, Li D, et al. Paeniclostridium sordellii hemorrhagic toxin targets TMPRSS2 to induce colonic epithelial lesions. Nat Commun. 2022;13:4331 pubmed publisher
immunocytochemistry; mouse western blot; mouse	Schael S, Nüchel J, Muller S, Petermann P, Kormann J, Pérez Otaño I, et al. Casein kinase 2 phosphorylation of protein kinase C and casein kinase 2 substrate in neurons (PACSIN) 1 protein regulates neuronal spine formation. J Biol Chem. 2013;288:9303-12 pubmed publisher
blocking or activating experiments; human	Bhanot H, Young A, Overmeyer J, Maltese W. Induction of nonapoptotic cell death by activated Ras requires inverse regulation of Rac1 and Arf6. Mol Cancer Res. 2010;8:1358-74 pubmed publisher
western blot; mouse; 1:1000	Godfrey E, Schwarte R. Nitric oxide and cyclic GMP regulate early events in agrin signaling in skeletal muscle cells. Exp Cell Res. 2010;316:1935-45 pubmed publisher
	Hezel M, de Groat W, Galbiati F. Caveolin-3 promotes nicotinic acetylcholine receptor clustering and regulates neuromuscular junction activity. Mol Biol Cell. 2010;21:302-10 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RACGAP1 Monoclonal Antibody (23A8)

Catalog # :

MA1-20580

Quantity :

50 ug

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Frozen): 10 ug/mL, Immunoprecipitation: 4 ug, Western Blot: 0.5-2 ug/mL

Species :

Human, Mouse, Rat

Clone :

23A8

Isotype :

IgG2b

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.

Immunogen :

Recombinant, full length, human RAC protein.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Frozen): 10 ug/mL, Immunoprecipitation: 4 ug, Western Blot: 0.5-2 ug/mL

Aliases :

AI227039; AI327394; AKT; Band25; CYK4; GAP; gtl11; GTPase; HsCYK-4; ID; ID-GAP; KIAA1478; Male germ cell RacGap; MGC99656; MgcRacGAP; mKIAA1478; PKB; PKB-ALPHA; PRKBA; protein CYK4 homolg; Protein CYK4 homolog; RAC; Rac GTPase activating protein 1; Rac GTPase-activating protein 1; RAC-ALPHA; Racgap1

more info or order :

Invitrogen product webpage