This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CCR5 Monoclonal Antibody (HEK/1/85a), FITC
catalog :
MA1-20282
quantity :
50 ug
price :
US 480.00
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
HEK/1/85a

The same clone is also sold as:
reactivity :
human, mouse
application :
flow cytometry
product information
Product Type :
Antibody
Product Name :
CCR5 Monoclonal Antibody (HEK/1/85a), FITC
Catalog # :
MA1-20282
Quantity :
50 ug
Price :
US 480.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Rat
Reactivity :
Human, Mouse
Applications :
Flow Cytometry: Neat-1:10 (10 uL/1x10^6 cells in 100 uL)
Species :
Human, Mouse
Clone :
HEK/1/85a
Isotype :
IgG2a
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles. Store in the dark.
Description :
Human immunodeficiency virus (HIV) and related virus require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. Among them, CCR5 (CC-CKR-5) is a principal coreceptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells. CCR5 is required for the infection by HIV-1, HIV-2, and SIV. The beta-chemokines RANTES, MIP-alpha and MIP-beta are the ligands for CCR5 and prevent infection by M-tropic HIV-1. CCR5 associates with the surface CD4-gp120 of HIV complex and leads to membrane fusion and virus entry of target cells. The amino-terminal domain and the extracellular loops of CCR5 serve as HIV biding sites. CCR5 messenger RNA is expressed in lymphoid organs and monocytes.
Immunogen :
Human CCR5 transfected into CHO cells.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Neat-1:10 (10 uL/1x10^6 cells in 100 uL)
Aliases :
AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; Cmkbr5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA