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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Angiogenin Monoclonal Antibody (14017.7)
catalog :
MA1-20177
quantity :
100 µg
price :
US 446.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
14017.7
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
more info or order :
Invitrogen product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:500
Gong B, Lee Y, Lee I, Shelite T, Kunkeaw N, Xu G, et al. Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: evidence of possible mediation by host tRNA-derived small noncoding RNAs. BMC Infect Dis. 2013;13:285 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Angiogenin Monoclonal Antibody (14017.7)
Catalog # :
MA1-20177
Quantity :
100 µg
Price :
US 446.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human
Applications :
ELISA: 2-8 µg/mL, Immunohistochemistry: 1:1,000, Western Blot: 1-2 µg/mL
Species :
Human
Clone :
14017.7
Isotype :
IgG1
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.
Immunogen :
Recombinant, full length, human angiogenin protein.
Format :
Liquid
Applications w/Dilutions :
ELISA: 2-8 µg/mL, Immunohistochemistry: 1:1,000, Western Blot: 1-2 µg/mL
Aliases :
AI385586; ALS9; ANG; Ang1; Angiogenin; angiogenin ribonuclease 1; angiogenin, ribonuclease A family, member 1; angiogenin, ribonuclease, RNase A family, 5; angiogenin-1; epididymis luminal protein 168; HEL168; MGC22466; MGC71966; RAA1; Ribonuclease 5; ribonuclease A A1; ribonuclease A family member 5; RNase 5; RNASE4; RNASE5; Rnase5a
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA