TOMM22 Monoclonal Antibody (1C9-2) | Invitrogen MA1-20161 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TOMM22 Monoclonal Antibody (1C9-2)

catalog :

MA1-20161

quantity :

50 uL

price :

US 484.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1C9-2

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:250	Dyllick Brenzinger M, D Souza C, Dahlmann B, Kloetzel P, Tandon A. Reciprocal effects of alpha-synuclein overexpression and proteasome inhibition in neuronal cells and tissue. Neurotox Res. 2010;17:215-27 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TOMM22 Monoclonal Antibody (1C9-2)

Catalog # :

MA1-20161

Quantity :

50 uL

Price :

US 484.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human, Non-human primate

Applications :

Immunocytochemistry: Assay-dependent, Immunomicroscopy: Assay-dependent, Western Blot: 0.5-1 ug/mL

Species :

Human, Non-human primate

Clone :

1C9-2

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Tom22 has a negatively charged N-terminal region exposed to the cytosol, a putative transmembrane region, and a C-terminal intermembrane space region with little negative charge. The following functions can be assigned to the three domains of Tom22: the cytosolic N-terminal domain plays a dual role, specifically important for presequence binding; the intermembrane space domain provides a trans binding site for presequences, and the single membrane anchor of Tom22 is crucial for the integrity of the GIP (general import gene) complex. The TOM complex of mammalian mitochondria resembles the fungal Tom complex, but is distinct from the plant TOM system. Thus, while unique components of the mammalian mitochondrial import system have been identified (e. g. TOM34 and metaxin), Tom22, and Tom37 have not been identified in plant mitochondria.

Immunogen :

Membrane fraction from Vero (monkey kidney-derived) cells.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-dependent, Immunomicroscopy: Assay-dependent, Western Blot: 0.5-1 ug/mL

Aliases :

1C9-2; 2310047D01; hTom22; Mitochondrial import receptor subunit TOM22 homolog; mitochondrial import receptor Tom22; MST065; MSTP065; rTOM22; Tom22; Tomm22; Translocase of outer membrane 22 kDa subunit homolog; translocase of outer mitochondrial membrane 22; translocase of outer mitochondrial membrane 22 homolog; translocase of outer mitochondrial membrane 22 homolog (yeast)

more info or order :

Invitrogen product webpage