Cardiac Troponin I Monoclonal Antibody (16A11) | Invitrogen MA1-20112 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cardiac Troponin I Monoclonal Antibody (16A11)

catalog :

MA1-20112

quantity :

200µg

price :

US 390

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

16A11

reactivity :

domestic goat, human, mouse, rat, dogs, chicken, bovine, pigs , zebrafish , cat

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - frozen section, immunohistochemistry - free floating section

more info or order :

Invitrogen product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; zebrafish ; 1:1000; loading ...; fig s1e	Wan Y, Wei Z, Looger L, Koyama M, Druckmann S, Keller P. Single-Cell Reconstruction of Emerging Population Activity in an Entire Developing Circuit. Cell. 2019;179:355-372.e23 pubmed publisher
immunohistochemistry - frozen section; zebrafish ; 1:100; loading ...; fig 3e	Lei L, Yan S, Yang R, Chen J, Li Y, Bu Y, et al. Spliceosomal protein eftud2 mutation leads to p53-dependent apoptosis in zebrafish neural progenitors. Nucleic Acids Res. 2017;45:3422-3436 pubmed publisher
immunohistochemistry; chicken; 1:100; loading ...	Nagy N, Barad C, Graham H, Hotta R, Cheng L, Fejszak N, et al. Sonic hedgehog controls enteric nervous system development by patterning the extracellular matrix. Development. 2016;143:264-75 pubmed publisher
immunohistochemistry - free floating section; zebrafish ; 1:500	Edelmann K, Glashauser L, Sprungala S, Hesl B, Fritschle M, Ninkovic J, et al. Increased radial glia quiescence, decreased reactivation upon injury and unaltered neuroblast behavior underlie decreased neurogenesis in the aging zebrafish telencephalon. J Comp Neurol. 2013;521:3099-115 pubmed publisher
immunohistochemistry - frozen section; zebrafish ; 1:400	Lindsey B, Darabie A, Tropepe V. The cellular composition of neurogenic periventricular zones in the adult zebrafish forebrain. J Comp Neurol. 2012;520:2275-316 pubmed publisher
immunohistochemistry - frozen section; zebrafish ; 1:100	Ampatzis K, Kentouri M, Dermon C. Neuronal and glial localization of alpha(2A)-adrenoceptors in the adult zebrafish (Danio rerio) brain. J Comp Neurol. 2008;508:72-93 pubmed publisher
	Libard S, Alafuzoff I. Alzheimer's disease neuropathological change and loss of matrix/neuropil in patients with idiopathic Normal Pressure Hydrocephalus, a model of Alzheimer's disease. Acta Neuropathol Commun. 2019;7:3 pubmed publisher
	Bern M, Parikh B, Yang L, Beckman D, Poursine Laurent J, Yokoyama W. Inducible down-regulation of MHC class I results in natural killer cell tolerance. J Exp Med. 2019;216:99-116 pubmed publisher
	Kaczmarek Hájek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, et al. Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody. elife. 2018;7: pubmed publisher
	Schredelseker T, Driever W. Bsx controls pineal complex development. Development. 2018;145: pubmed publisher
	Baek C, Freem L, Goïame R, Sang H, Morin X, Tozer S. Mib1 prevents Notch Cis-inhibition to defer differentiation and preserve neuroepithelial integrity during neural delamination. PLoS Biol. 2018;16:e2004162 pubmed publisher
	Quatrini L, Wieduwild E, Guia S, Bernat C, Glaichenhaus N, Vivier E, et al. Host resistance to endotoxic shock requires the neuroendocrine regulation of group 1 innate lymphoid cells. J Exp Med. 2017;214:3531-3541 pubmed publisher
	Bern M, Beckman D, Ebihara T, Taffner S, Poursine Laurent J, White J, et al. Immunoreceptor tyrosine-based inhibitory motif-dependent functions of an MHC class I-specific NK cell receptor. Proc Natl Acad Sci U S A. 2017;114:E8440-E8447 pubmed publisher
	Gau P, Curtright A, Condon L, Raible D, Dhaka A. An ancient neurotrophin receptor code; a single Runx/Cbf? complex determines somatosensory neuron fate specification in zebrafish. PLoS Genet. 2017;13:e1006884 pubmed publisher
	Evans A, Moser J, Krug L, Pozharskaya V, Mora A, Speck S. A gammaherpesvirus-secreted activator of Vbeta4+ CD8+ T cells regulates chronic infection and immunopathology. J Exp Med. 2008;205:669-84 pubmed publisher
	McWhorter M, Monani U, Burghes A, Beattie C. Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding. J Cell Biol. 2003;162:919-31 pubmed

product information

Product Type :

Antibody

Product Name :

Cardiac Troponin I Monoclonal Antibody (16A11)

Catalog # :

MA1-20112

Quantity :

200µg

Price :

US 390

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Bovine, Canine, Feline, Goat, Human, Mouse, Porcine, Rabbit, Rat

Applications :

Affinity Purification: Assay Dependent, ELISA: Assay dependent, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1:500

Species :

Bovine, Canine, Feline, Goat, Human, Mouse, Porcine, Rabbit, Rat

Clone :

16A11

Isotype :

IgG1

Storage :

4° C

Description :

Cardiac Troponin I (Cardiac-specific troponin I, TnI, Troponin I) is an integral inhibitory protein in cardiac muscle that exists as part of a complex with troponin C (TnC) and troponin T (TnT). The TnT subunit of troponin binds to tropomyosin-t form, a troponin-tropomyosin complex, anchored in place by the binding of TnI to actin, within muscle thin filaments. Structural change resulting from the binding of calcium to specific sites on the regulatory TnC subunit, releases the inhibitory region of TnI from actin, anabling the attachment of the molecular motor protein myosin, allowing for muscle contraction and hence movement. The measurements of blood TnI and TnT levels is an important diagnostics indicator of heart muscle damage, and can be used to differentiate between angina and myocardial infarction in patients with chest pains. Cardiac Troponin I has also been shown to inhibit angiogenesis in vivo and in vitro. Mutations in the Cardiac Troponin I gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

Immunogen :

Full length, human cardiac troponin 1 protein.

Format :

Liquid

Applications w/Dilutions :

Affinity Purification: Assay Dependent, ELISA: Assay dependent, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1:500

Aliases :

BOS_18114; Cardiac troponin I; cardiac troponin I isoform; cardiomyopathy, dilated 2A (autosomal recessive); CMD1FF; CMD2A; CMH7; Ctni; LOC511094; MGC116817; RCM1; Tn1; Tni; TNNC1; Tnni3; Tpn1; troponin 1, type 3; troponin I type 3 (cardiac); troponin I, cardiac 3; Troponin I, cardiac muscle; troponin I, cardiac muscle-like; troponin I3, cardiac type

more info or order :

Invitrogen product webpage