Myeloperoxidase Monoclonal Antibody (4A4) | Invitrogen MA1-20074 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Myeloperoxidase Monoclonal Antibody (4A4)

catalog :

MA1-20074

quantity :

100 ug

price :

US 464.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4A4

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:100	Appel H, Maier R, Bleil J, Hempfing A, Loddenkemper C, Schlichting U, et al. In situ analysis of interleukin-23- and interleukin-12-positive cells in the spine of patients with ankylosing spondylitis. Arthritis Rheum. 2013;65:1522-9 pubmed publisher
immunohistochemistry; mouse	Atkinson W, Forghani R, Wojtkiewicz G, Pulli B, Iwamoto Y, Ueno T, et al. Ligation of the jugular veins does not result in brain inflammation or demyelination in mice. PLoS ONE. 2012;7:e33671 pubmed publisher
immunohistochemistry; rat	Varnalidis I, Ioannidis O, Karamanavi E, Ampas Z, Poutahidis T, Taitzoglou I, et al. Omega 3 fatty acids supplementation has an ameliorative effect in experimental ulcerative colitis despite increased colonic neutrophil infiltration. Rev Esp Enferm Dig. 2011;103:511-8 pubmed
immunohistochemistry; rat	Kleijn A, Chen J, Buhrman J, Wojtkiewicz G, Iwamoto Y, Lamfers M, et al. Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging. Clin Cancer Res. 2011;17:4484-93 pubmed publisher
immunohistochemistry; mouse	El Sayed N, Mahran L, Khattab M. Tempol, a membrane-permeable radical scavenger, ameliorates lipopolysaccharide-induced acute lung injury in mice: a key role for superoxide anion. Eur J Pharmacol. 2011;663:68-73 pubmed publisher
immunohistochemistry; rat; 1:200	Belli S, Basaran O, Ozdemir B, Turkoglu S, Karabay G, Kut A, et al. Protective role of simvastatin on lung damage caused by burn and cotton smoke inhalation in rats. J Surg Res. 2011;167:e283-90 pubmed publisher
immunohistochemistry; human	Zini E, Osto M, Moretti S, Franchini M, Kook P, Lutz H, et al. Hyperglycaemia but not hyperlipidaemia decreases serum amylase and increases neutrophils in the exocrine pancreas of cats. Res Vet Sci. 2010;89:20-6 pubmed publisher
immunohistochemistry; mouse	Marmon S, Hinchey J, Oh P, Cammer M, de Almeida C, Gunther L, et al. Caveolin-1 expression determines the route of neutrophil extravasation through skin microvasculature. Am J Pathol. 2009;174:684-92 pubmed publisher
immunohistochemistry; mouse	Kao J, Rathinavelu S, Eaton K, Bai L, Zavros Y, Takami M, et al. Helicobacter pylori-secreted factors inhibit dendritic cell IL-12 secretion: a mechanism of ineffective host defense. Am J Physiol Gastrointest Liver Physiol. 2006;291:G73-81 pubmed
immunohistochemistry; human	Gulkarov I, Pintucci G, Bohmann K, Saunders P, Sullivan R, Ferrari G, et al. Mechanisms of c-reactive protein up-regulation in arterialized vein grafts. Surgery. 2006;139:254-62 pubmed
	Chuang J, Chang N, Huang C, Lo S, Wang H, Chen C, et al. Biliary intervention augments chemotactic reaction and aggravates cholestatic liver injury in rats. J Surg Res. 2004;120:210-8 pubmed

product information

Product Type :

Antibody

Product Name :

Myeloperoxidase Monoclonal Antibody (4A4)

Catalog # :

MA1-20074

Quantity :

100 ug

Price :

US 464.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Affinity Purification: Assay-dependent, ELISA: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Clone :

4A4

Isotype :

IgG2b

Storage :

4 C, do not freeze

Description :

Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.

Immunogen :

Purified, full length, native, human myeloperoxidase protein.

Format :

Liquid

Applications w/Dilutions :

Affinity Purification: Assay-dependent, ELISA: Assay-dependent, Western Blot: Assay-dependent

Aliases :

84 kDa myeloperoxidase; 89 kDa myeloperoxidase; mKIAA4033; MPO; Myeloperoxidase; Myeloperoxidase heavy chain; Myeloperoxidase light chain

more info or order :

Invitrogen product webpage