HNF4A Monoclonal Antibody (K9218) | Invitrogen MA1-199 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HNF4A Monoclonal Antibody (K9218)

catalog :

MA1-199

quantity :

100 uL

price :

US 524.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

K9218

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; mouse; loading ...; fig 3c immunocytochemistry; mouse; loading ...; fig 6a western blot; mouse; loading ...; fig 1b	Bi Y, Shi X, Zhu J, Guan X, Garbacz W, Huang Y, et al. Regulation of Cholesterol Sulfotransferase SULT2B1b by Hepatocyte Nuclear Factor 4α Constitutes a Negative Feedback Control of Hepatic Gluconeogenesis. Mol Cell Biol. 2018;38: pubmed publisher
	Gerardo Ram xed rez M, Giam V, Becker D, Groth M, Hartmann N, Morrison H, et al. Deletion of Cd44 Inhibits Metastasis Formation of Liver Cancer in Nf2-Mutant Mice. Cells. 2023;12: pubmed publisher
	Lee H, Jang H, Li H, Samuel V, Dudek K, Osipovich A, et al. Deletion of Jazf1 gene causes early growth retardation and insulin resistance in mice. Proc Natl Acad Sci U S A. 2022;119:e2213628119 pubmed publisher
	Xu J, Kausalya P, Ong A, Goh C, Mohamed Ali S, Hunziker W. ZO-2/Tjp2 suppresses Yap and Wwtr1/Taz-mediated hepatocyte to cholangiocyte transdifferentiation in the mouse liver. NPJ Regen Med. 2022;7:55 pubmed publisher
	Richards A, Friesen M, Khalil A, Barrasa M, Gehrke L, Jaenisch R. SARS-CoV-2 infection of human pluripotent stem cell-derived liver organoids reveals potential mechanisms of liver pathology. iScience. 2022;25:105146 pubmed publisher
	Wu B, Mei S, Chen E, Zheng Y, Pan D. YAP induces an oncogenic transcriptional program through TET1-mediated epigenetic remodeling in liver growth and tumorigenesis. Nat Genet. 2022;54:1202-1213 pubmed publisher
	Bonanini F, Kurek D, Previdi S, Nicolas A, Hendriks D, de Ruiter S, et al. In vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bed. Angiogenesis. 2022;25:455-470 pubmed publisher
	Wilson S, Howden S, Vanslambrouck J, Dorison A, Alquicira Hernández J, Powell J, et al. DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets. Genome Med. 2022;14:19 pubmed publisher
	Hansen J, Loell K, Cohen B. A test of the pioneer factor hypothesis using ectopic liver gene activation. elife. 2022;11: pubmed publisher
	Mori A, Murata S, Tashiro N, Tadokoro T, Okamoto S, Otsuka R, et al. Establishment of Human Leukocyte Antigen-Mismatched Immune Responses after Transplantation of Human Liver Bud in Humanized Mouse Models. Cells. 2021;10: pubmed publisher
	Tun xe7 er S, Sade Memi x15f o x11f lu A, Ke x15f k xfc x15f A, Sheraj I, G xfc ner G, Akyol A, et al. Enhanced expression of HNF4α during intestinal epithelial differentiation is involved in the activation of ER stress. FEBS J. 2020;287:2504-2523 pubmed publisher
	An Y, Wang P, Xu P, Tung H, Xie Y, Kirisci L, et al. An Unexpected Role of Cholesterol Sulfotransferase and its Regulation in Sensitizing Mice to Acetaminophen-Induced Liver Injury. Mol Pharmacol. 2019;95:597-605 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HNF4A Monoclonal Antibody (K9218)

Catalog # :

MA1-199

Quantity :

100 uL

Price :

US 524.00

Clonality :

Monoclonal

Purity :

Ammonium sulfate precipitation

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 0.1 ug/mL, Flow Cytometry: 1-20 ug/mL, Immunocytochemistry: 1:100-1:2,000, Immunohistochemistry (Paraffin): 10-20 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: 1 ug/mL

Species :

Human, Mouse, Rat

Clone :

K9218

Isotype :

IgG2a

Storage :

Maintain refrigerated at 2-8 C for up to 1 month. For long term storage store at -20 C

Description :

Hepatocyte nuclear factor 4 alpha (HNF4 alpha) is an orphan nuclear receptor. HNF4a is expressed in the liver, kidney, intestine, and pancreas. Mutation of HNF4a in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4a gene is alternatively spliced and may generate up to nine different isoforms, HNF4a1 through HNF4a9.

Immunogen :

Baculovirus-expressed recombinant human HNF4 alpha (aa 3-49)

Format :

Liquid

Applications w/Dilutions :

ELISA: 0.1 ug/mL, Flow Cytometry: 1-20 ug/mL, Immunocytochemistry: 1:100-1:2,000, Immunohistochemistry (Paraffin): 10-20 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: 1 ug/mL

Aliases :

alpha transcription factor 4; FLJ39654; FRTS4; hepatic nuclear factor 4 alpha; hepatic nuclear factor 4, alpha; hepatocyte nuclear factor 4 alpha; hepatocyte nuclear factor 4, alpha; hepatocyte nuclear factor 4-alpha; HNF4; Hnf-4; HNF4 alpha; Hnf4a; HNF4a7; HNF4a8; HNF4a9; Hnf4alpha; HNF-4-alpha; HNF4-alpha; HNF4alpha10; HNF4alpha10/11/12; HNF4alpha11; HNF4alpha12; MODY; MODY1; NR2A1; NR2A21; Nuclear receptor 2A1; nuclear receptor subfamily 2 group A member 1; TCF; TCF14; TCF-14; Transcription factor 14; transcription factor HNF-4

more info or order :

Invitrogen product webpage