This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD63 Monoclonal Antibody (MEM-259), PE
catalog :
MA1-19650
quantity :
100 Tests
price :
US 491.00
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
MEM-259

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 3
Reference
Machala M, Slav xed k J, Kov xe1 x10d O, Proch xe1 zkov xe1 J, P x11b n x10d xed kov xe1 K, Pa x159 enicov xe1 M, et al. Changes in Sphingolipid Profile of Benzo[a]pyrene-Transformed Human Bronchial Epithelial Cells Are Reflected in the Altered Composition of Sphingolipids in Their Exosomes. Int J Mol Sci. 2021;22: pubmed publisher
Görgens A, Bremer M, Ferrer Tur R, Murke F, Tertel T, Horn P, et al. Optimisation of imaging flow cytometry for the analysis of single extracellular vesicles by using fluorescence-tagged vesicles as biological reference material. J Extracell Vesicles. 2019;8:1587567 pubmed publisher
Malla B, Aebersold D, Dal Pra A. Protocol for serum exosomal miRNAs analysis in prostate cancer patients treated with radiotherapy. J Transl Med. 2018;16:223 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD63 Monoclonal Antibody (MEM-259), PE
Catalog # :
MA1-19650
Quantity :
100 Tests
Price :
US 491.00
Clonality :
Monoclonal
Purity :
Size-exclusion chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 20 uL x 100 uL whole blood or 10^6 cells
Species :
Human
Clone :
MEM-259
Isotype :
IgG1
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. CD63 is also present in the plasma membrane, usually following cell activation. Hence, CD63 has become a widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas. CD63 is expressed on activated platelets, and is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation. CD63 is also present in monocytes and macrophages and is weakly expressed on granulocytes, B, and T cells. CD63 is identical to the melanoma-associated antigen which is ME491 and to the platelet antigen PTLGP40. Diseases associated with CD63 dysfunction include melanoma and Hermansky-Pudlak Syndrome.
Immunogen :
T cell line HPB-ALL.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 20 uL x 100 uL whole blood or 10^6 cells
Aliases :
C75951; CD 63; Cd63; CD63 antigen; CD63 antigen (melanoma 1 antigen); Cd63 molecule; CD63 protein; granulophysin; LAMP-3; Lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; mast cell antigen AD1; ME491; melanoma 1 antigen; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; Ocular melanoma-associated antigen; OMA81H; Tetraspanin-30; TSPAN30; tspan-30
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA