CD56 Monoclonal Antibody (MEM-188), PE | Invitrogen MA1-19638 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD56 Monoclonal Antibody (MEM-188), PE

catalog :

MA1-19638

quantity :

100 Tests

price :

US 421.00

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

MEM-188

reactivity :

human, mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse	Mokbel N, Hoffman N, Girgis C, Small L, Turner N, Daly R, et al. Grb10 deletion enhances muscle cell proliferation, differentiation and GLUT4 plasma membrane translocation. J Cell Physiol. 2014;229:1753-64 pubmed publisher
flow cytometry; human; fig 1	Elsner L, Flügge P, Lozano J, Muppala V, Eiz Vesper B, Demiroglu S, et al. The endogenous danger signals HSP70 and MICA cooperate in the activation of cytotoxic effector functions of NK cells. J Cell Mol Med. 2010;14:992-1002 pubmed publisher
flow cytometry; human	Mageed A, Pietryga D, DeHeer D, West R. Isolation of large numbers of mesenchymal stem cells from the washings of bone marrow collection bags: characterization of fresh mesenchymal stem cells. Transplantation. 2007;83:1019-26 pubmed
	Singh Y, Trautwein C, Fendel R, Krickeberg N, Berezhnoy G, Bissinger R, et al. SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells. Heliyon. 2021;7:e07147 pubmed publisher

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product information

Product Type :

Antibody

Product Name :

CD56 Monoclonal Antibody (MEM-188), PE

Catalog # :

MA1-19638

Quantity :

100 Tests

Price :

US 421.00

Clonality :

Monoclonal

Purity :

Size-exclusion chromatography

Host :

Mouse

Reactivity :

Human, Non-human primate

Applications :

Flow Cytometry: 20 µL/100 µL whole blood

Species :

Human, Non-human primate

Clone :

MEM-188

Isotype :

IgG2a

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.

Immunogen :

KG-1 human acute myelogenous leukaemia cell line.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 20 µL/100 µL whole blood

Aliases :

adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM

more info or order :

Invitrogen product webpage