ICAM-1 Monoclonal Antibody (1H4), FITC | Invitrogen MA1-19616 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ICAM-1 Monoclonal Antibody (1H4), FITC

catalog :

MA1-19616

quantity :

100 tests

price :

US 358

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

1H4

reactivity :

human

application :

flow cytometry

citations: 2

Reference
Nomoto Kojima N, Aoki S, Uchihashi K, Matsunobu A, Koike E, Ootani A, et al. Interaction between adipose tissue stromal cells and gastric cancer cells in vitro. Cell Tissue Res. 2011;344:287-98 pubmed publisher
Udo K, Aoki S, Uchihashi K, Kawasaki M, Matsunobu A, Tokuda Y, et al. Adipose tissue explants and MDCK cells reciprocally regulate their morphogenesis in coculture. Kidney Int. 2010;78:60-8 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ICAM-1 Monoclonal Antibody (1H4), FITC

Catalog # :

MA1-19616

Quantity :

100 tests

Price :

US 358

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 20 µL x 100 µL whole blood or 10^6 cells

Species :

Human

Clone :

1H4

Isotype :

IgG2b

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.

Immunogen :

Raji cells and spleen cells fused with NS1 cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 20 µL x 100 µL whole blood or 10^6 cells

Aliases :

BB2; CD54; cell surface glycoprotein P3.58; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; intercellular adhesion molecule-like; LOC100345640; Ly-47; Major group rhinovirus receptor; MALA-2; MyD10; P3.58; sCD54; soluble CD54