CD80 Monoclonal Antibody (MEM-233), FITC | Invitrogen MA1-19590 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD80 Monoclonal Antibody (MEM-233), FITC

catalog :

MA1-19590

quantity :

100 Tests

price :

US 412.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

MEM-233

reactivity :

human

application :

immunocytochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; tbl 2 immunocytochemistry; human; fig 2d	Sandilands G, McCrae J, Hill K, Perry M, Baxter D. Major histocompatibility complex class II (DR) antigen and costimulatory molecules on in vitro and in vivo activated human polymorphonuclear neutrophils. Immunology. 2006;119:562-71 pubmed
flow cytometry; human	Zingoni A, Sornasse T, Cocks B, Tanaka Y, Santoni A, Lanier L. Cross-talk between activated human NK cells and CD4+ T cells via OX40-OX40 ligand interactions. J Immunol. 2004;173:3716-24 pubmed
flow cytometry; human; fig 1	Vasu C, Wang A, Gorla S, Kaithamana S, Prabhakar B, Holterman M. CD80 and CD86 C domains play an important role in receptor binding and co-stimulatory properties. Int Immunol. 2003;15:167-75 pubmed
	Wang W, Pan D, Fu W, Ye X, Han J, Yang L, et al. Development of a skin- and neuro-attenuated live vaccine for varicella. Nat Commun. 2022;13:824 pubmed publisher

image

image 1 :

product information

Product Type :

Antibody

Product Name :

CD80 Monoclonal Antibody (MEM-233), FITC

Catalog # :

MA1-19590

Quantity :

100 Tests

Price :

US 412.00

Clonality :

Monoclonal

Purity :

Size-exclusion chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 20 µL/100 µL whole blood

Species :

Human

Clone :

MEM-233

Isotype :

IgG1

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

Immunogen :

Extracellular domain of human CD80 fused to human IgG1(Fc).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 20 µL/100 µL whole blood

Aliases :

Activation B7-1 antigen; B7; B7 protein; B7.1; B71; B7-1; B7-1 protein; B7-1 protein precursor; BB1; B-lymphocyte activation antigen B7; Cd28l; CD28LG; CD28LG1; CD80; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); CD80 anitgen; CD80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); Cd80 molecule; CD80 protein precursor; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; Ly53; Ly-53; MIC17; sCD 80; sCD80; secreted B7-1 protein precursor; soluble CD 80; soluble CD80; T-cell costimulatory molecule; T-cell co-stimulatory protein B7-1; T-lymphocyte activation antigen CD80; TS/A-1; TSA1

more info or order :

Invitrogen product webpage