CD31 Monoclonal Antibody (MEM-05), Biotin | Invitrogen MA1-19510 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD31 Monoclonal Antibody (MEM-05), Biotin

catalog :

MA1-19510

quantity :

100 ug

price :

US 426.00

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

MEM-05

The same clone is also sold as:

Abcam: ab187594
Exbio: T5-273-T100, 1A-273-T025, PC-273-T100, 1P-273-T100, PB-273-T100, T8-273-T025, 1A-273-T100, PC-273-T025, PB-273-T025, 11-273-C100, 1B-273-C100, T8-273-T100, 1P-273-T025, A4-273-T025, 1F-273-T100, 1B-273-C025, T5-273-T025, A4-273-T100, 1F-273-T025, 11-273-C025
OriGene: BM4047, BM4047S, BM4047F, BM4047APC, BM4047B, BM4047R, BM4047PP

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 2

Reference
Abner E, Elahi F, Jicha G, Mustapic M, Al Janabi O, Kramer J, et al. Endothelial-derived plasma exosome proteins in Alzheimer's disease angiopathy. FASEB J. 2020;34:5967-5974 pubmed publisher
Mahajan K, Nabar G, Xue W, Anghelina M, Moldovan N, Chalmers J, et al. Mechanotransduction Effects on Endothelial Cell Proliferation via CD31 and VEGFR2: Implications for Immunomagnetic Separation. Biotechnol J. 2017;12: pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD31 Monoclonal Antibody (MEM-05), Biotin

Catalog # :

MA1-19510

Quantity :

100 ug

Price :

US 426.00

Clonality :

Monoclonal

Purity :

Size-exclusion chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 2-4 ug/mL, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Clone :

MEM-05

Isotype :

IgG1

Storage :

4 C, do not freeze

Description :

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

Immunogen :

Leukocytes from a patient suffering from a LGL type leukaemia.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 2-4 ug/mL, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-dependent

Aliases :

C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule