This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
LIME Monoclonal Antibody (LIME-06)
catalog :
MA1-19365
quantity :
100 ug
price :
US 414.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
LIME-06

The same clone is also sold as:
reactivity :
human
application :
immunoprecipitation, flow cytometry
product information
Product Type :
Antibody
Product Name :
LIME Monoclonal Antibody (LIME-06)
Catalog # :
MA1-19365
Quantity :
100 ug
Price :
US 414.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 8-12 ug/mL, Immunoprecipitation: Assay-dependent
Species :
Human
Clone :
LIME-06
Isotype :
IgG1, kappa
Storage :
4 C, do not freeze
Description :
LIME (Lck-interacting molecule) is a 30 kDa double-palmitoylated protein with unusually basic cytoplasmic domain, expressed by T cells. After ligation of CD4 or CD8 T cell coreceptors, LIME is phosphorylated by Src-family kinases and associates with Lck and Fyn kinases and with their negative regulator Csk. Interestingly, Csk-mediated phosphorylation of C-terminal negative-regulatory tyrosine of LIME-associated Lck can result in increase of enzymatic activity compared with the total pool of Lck, thus, LIME serves as a positive regulator of TCR-dependent T cell signaling. However, under some circumstances, LIME may mediate inhibitory signals.
Immunogen :
Bacterially expressed intracellular fragment corresponding to aa 141-295 of human LIME
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 8-12 ug/mL, Immunoprecipitation: Assay-dependent
Aliases :
2810038K19Rik; dJ583P15.4; FLJ20406; Lck interacting transmembrane adaptor 1; lck-interacting membrane protein; Lck-interacting molecule; lck-interacting transmembrane adapter 1; Lime; lime 1; LIME1; LP8067; RP4-583P15.5
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA