Kinesin 5B Monoclonal Antibody (KN-02) | Invitrogen MA1-19352 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Kinesin 5B Monoclonal Antibody (KN-02)

catalog :

MA1-19352

quantity :

100 µg

price :

US 436

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

KN-02

reactivity :

human, mouse, rat, pigs

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; rat; 1:500; fig 10 immunohistochemistry; human; 1:500; fig 5	Chu Y, Morfini G, Kordower J. Alterations in Activity-Dependent Neuroprotective Protein in Sporadic and Experimental Parkinson's Disease. J Parkinsons Dis. 2016;6:77-97 pubmed publisher

image

image 1 :

Immunofluorescence analysis of Rat Basophils (RBL-2H3 leukemic cell line) stained with MA1-19352 followed by a fluorescently conjugated secondary antibody. MA1-19352 stained vesicles are shown in red, and DAPI nuclear stainning is shown in blue.

image 2 :

Rat hippocampus stained with MA1-19352 antibody. Free-floating sections were incubated with MA1-19352 at 1:250 dilution overnight followed by goat anti-mouse conjugated to Cy2 for one hour. Sections were fixed with 4% paraffin. Data courtesy of the Innovators Program.

product information

Product Type :

Antibody

Product Name :

Kinesin 5B Monoclonal Antibody (KN-02)

Catalog # :

MA1-19352

Quantity :

100 µg

Price :

US 436

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human, Mouse, Porcine, Rat

Applications :

Immunocytochemistry: Assay Dependent, Immunohistochemistry (Paraffin): Assay Dependent

Species :

Human, Mouse, Porcine, Rat

Clone :

KN-02

Isotype :

IgM

Storage :

4° C, do not freeze

Description :

Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.

Immunogen :

Enriched fraction of porcine brain kinesin.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay Dependent, Immunohistochemistry (Paraffin): Assay Dependent

Aliases :

AL022807; Conventional kinesin heavy chain; EMBL:ABC25059.1}; epididymis secretory protein Li 61; HEL-S-61; Khc; Khcs; Kif5b; kif5b {ECO:0000312; kinesin 1 (110-120kD); kinesin family member 5B; kinesin heavy chain; kinesin heavy chain member 5B, ubiquitous; kinesin-1 heavy chain; KINH; KNS; KNS1; Ubiquitous kinesin heavy chain; UKHC; U-KHC

more info or order :

Invitrogen product webpage