Vimentin Monoclonal Antibody (VI-RE/1) | Invitrogen MA1-19319 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Vimentin Monoclonal Antibody (VI-RE/1)

catalog :

MA1-19319

quantity :

100 ug

price :

US 436.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

VI-RE/1

The same clone is also sold as:

Exbio: 1P-369-C025, 1A-369-C100, 1P-369-C100, 11-369-C100, 11-369-C025, 1A-369-C025
Abcam: ab49918, ab176512
OriGene: SM3129P, SM3129APC, SM3129R

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Sphyris N, King C, Hoar J, Werden S, Vijay G, Miura N, et al. Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth. Oncotarget. 2021;12:823-844 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Vimentin Monoclonal Antibody (VI-RE/1)

Catalog # :

MA1-19319

Quantity :

100 ug

Price :

US 436.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Flow Cytometry: 1-4 ug/mL, Immunocytochemistry: 5-10 ug/mL, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1-2 ug/mL

Species :

Human

Clone :

VI-RE/1

Isotype :

IgG1

Storage :

4 C, do not freeze

Description :

Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development. During the development process, vimentin is exchanged for new, tissue-specific IFPs. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.

Immunogen :

Bacterially expressed full-length human vimentin

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Flow Cytometry: 1-4 ug/mL, Immunocytochemistry: 5-10 ug/mL, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1-2 ug/mL

Aliases :

cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus