HLA-E Monoclonal Antibody (MEM-E/02) | Invitrogen MA1-19309 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HLA-E Monoclonal Antibody (MEM-E/02)

catalog :

MA1-19309

quantity :

100 µg

price :

US 450

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MEM-E/02

reactivity :

human, rhesus macaque

application :

western blot, ELISA, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human immunohistochemistry; human; 1:100	Sasaki T, Ravindranath M, Terasaki P, Freitas M, Kawakita S, Jucaud V. Gastric cancer progression may involve a shift in HLA-E profile from an intact heterodimer to ?2-microglobulin-free monomer. Int J Cancer. 2014;134:1558-70 pubmed publisher
immunohistochemistry - paraffin section; rhesus macaque; 1:100; fig 2	Nakayama K, Lee C, Batchelder C, Tarantal A. Tissue specificity of decellularized rhesus monkey kidney and lung scaffolds. PLoS ONE. 2013;8:e64134 pubmed publisher
flow cytometry; human western blot; human	Ravindranath M, Pham T, Ozawa M, Terasaki P. Antibodies to HLA-E may account for the non-donor-specific anti-HLA class-Ia antibodies in renal and liver transplant recipients. Int Immunol. 2012;24:43-57 pubmed publisher
ELISA; human; 1:600	Ravindranath M, Taniguchi M, Chen C, Ozawa M, Kaneku H, El Awar N, et al. HLA-E monoclonal antibodies recognize shared peptide sequences on classical HLA class Ia: relevance to human natural HLA antibodies. Mol Immunol. 2010;47:1121-31 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HLA-E Monoclonal Antibody (MEM-E/02)

Catalog # :

MA1-19309

Quantity :

100 µg

Price :

US 450

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Non-human primate

Applications :

Immunohistochemistry (Paraffin): 5-10 µg/mL, Western Blot: Assay Dependent

Species :

Human, Non-human primate

Clone :

MEM-E/02

Isotype :

IgG1

Storage :

4° C, do not freeze

Description :

HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

Immunogen :

Recombinant human HLA-E denaturated heavy chain.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 5-10 µg/mL, Western Blot: Assay Dependent

Aliases :

DAMA-277I14.1; DAQB-90C11.16; DKFZp686P19218; EA1.2; EA2.1; FLJ26655; HLA class I histocompatibility antigen, alpha chain E; HLA class I histocompatibility antigen, E alpha chain; HLA-6.2; HLAE; HLA-E; lymphocyte antigen; major histocompatibility complex, class I, E; MHC; MHC 1; MHC class I antigen E; MHC HLA-E alpha-1; MHC HLA-E alpha-2.1; MHC1; QA1; sHLA-E; Soluble HLA class I histocompatibility antigen, alpha chain E

more info or order :

Invitrogen product webpage