EBP50 Monoclonal Antibody (EBP-10) | Invitrogen MA1-19291 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EBP50 Monoclonal Antibody (EBP-10)

catalog :

MA1-19291

quantity :

100 µg

price :

US 500

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

EBP-10

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:400	Bartholow T, Becich M, Chandran U, Parwani A. Immunohistochemical analysis of ezrin-radixin-moesin-binding phosphoprotein 50 in prostatic adenocarcinoma. BMC Urol. 2011;11:12 pubmed publisher

product information

Product Type :

Antibody

Product Name :

EBP50 Monoclonal Antibody (EBP-10)

Catalog # :

MA1-19291

Quantity :

100 µg

Price :

US 500

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 5 µg/mL, Immunoprecipitation: Assay Dependent, Western Blot: 2 µg/mL

Species :

Human

Clone :

EBP-10

Isotype :

IgG2b

Storage :

4° C, do not freeze

Description :

NHERF1 (Na+/H+ exchanger regulatory factor 1), also known as EBP50 (ezrin, radixin, moesin-binding phosphoprotein 50) is an adaptor protein, which associates with beta-catenin and is required for its localization at the cell-cell junctions, interacts with various G protein-coupled receptors and regulates their traffic, as well as sodium-hydrogen exchange and sodium-dependent phosphate transport. NHERF1/EBP50 inhibits cell motility and is required to suppress anchorage-independent growth. It contains C-terminal ERM (ezrin, radixin, moesin)-binding region and two N-terminal PDZ (postsynaptic-density-95/disc-large/ZO1 homology) domains and is able to form head-to-tail intramolecular conformation to regulate its interactions.

Immunogen :

Bacterially produced, recombinant, full-length human NHERF1.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 5 µg/mL, Immunoprecipitation: Assay Dependent, Western Blot: 2 µg/mL

Aliases :

EBP50; EBP-50; ERM-binding phosphoprotein; ezrin-radixin-moesin binding phosphoprotein-50; ezrin-radixin-moesin-binding phosphoprotein 50; Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Na+/H+ exchange regulatory co-factor; NHERF; NHE-RF; NHERF1; NHERF-1; NPHLOP2; Regulatory cofactor of Na(+)/H(+) exchanger; SLC9A3 regulator 1; SLC9A3R1; So; Sodium-hydrogen exchanger regulatory factor 1; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1; solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1; solute carrier family 9 isoform A3 regulatory factor 1; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1

more info or order :

Invitrogen product webpage