CD177 Monoclonal Antibody (MEM-166) | Invitrogen MA1-19250 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD177 Monoclonal Antibody (MEM-166)

catalog :

MA1-19250

quantity :

100 µg

price :

US 299

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MEM-166

reactivity :

human

application :

western blot, immunoprecipitation, flow cytometry

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 4	O Brien E, Abdulahad W, Rutgers A, Huitema M, O Reilly V, Coughlan A, et al. Intermediate monocytes in ANCA vasculitis: increased surface expression of ANCA autoantigens and IL-1Î² secretion in response to anti-MPO antibodies. Sci Rep. 2015;5:11888 pubmed publisher
flow cytometry; human; fig 5	Li Y, Mair D, Schuller R, Li L, Wu J. Genetic mechanism of human neutrophil antigen 2 deficiency and expression variations. PLoS Genet. 2015;11:e1005255 pubmed publisher

image

image 1 :

product information

Product Type :

Antibody

Product Name :

CD177 Monoclonal Antibody (MEM-166)

Catalog # :

MA1-19250

Quantity :

100 µg

Price :

US 299

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Non-human primate

Applications :

Flow Cytometry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Species :

Human, Non-human primate

Clone :

MEM-166

Isotype :

IgG1

Storage :

4° C, do not freeze

Description :

CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).

Immunogen :

Human granulocytes.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Aliases :

1190003K14Rik; Cd177; CD177 antigen; CD177 molecule; cell surface receptor; HNA2A; HNA-2a; Human neutrophil alloantigen 2a; NB1; NB1 glycoprotein; NB1 GP; Pdp3; Polycythemia rubra vera protein 1; PRV1; PRV-1; RGD1562941; UNQ595/PRO1181

more info or order :

Invitrogen product webpage