CD14 Monoclonal Antibody (B-A8) | Invitrogen MA1-19240 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD14 Monoclonal Antibody (B-A8)

catalog :

MA1-19240

quantity :

100 µg

price :

US 366

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

B-A8

reactivity :

human

application :

ELISA, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Paupert J, Mansat De Mas V, Demur C, Salles B, Muller C. Cell-surface MMP-9 regulates the invasive capacity of leukemia blast cells with monocytic features. Cell Cycle. 2008;7:1047-53 pubmed
flow cytometry; human	Semnani R, Sabzevari H, Iyer R, Nutman T. Filarial antigens impair the function of human dendritic cells during differentiation. Infect Immun. 2001;69:5813-22 pubmed
flow cytometry; human; fig 2	Matasic R, Dietz A, Vuk Pavlovic S. Maturation of human dendritic cells as sulfasalazine target. Croat Med J. 2001;42:440-5 pubmed
flow cytometry; human	Matasic R, Dietz A, Vuk Pavlovic S. Cyclooxygenase-independent inhibition of dendritic cell maturation by aspirin. Immunology. 2000;101:53-60 pubmed
flow cytometry; human	McRae B, Nagai T, Semnani R, van Seventer J, van Seventer G. Interferon-alpha and -beta inhibit the in vitro differentiation of immunocompetent human dendritic cells from CD14(+) precursors. Blood. 2000;96:210-7 pubmed
	Harvey H, Post D, Apicella M. Immortalization of human urethral epithelial cells: a model for the study of the pathogenesis of and the inflammatory cytokine response to Neisseria gonorrhoeae infection. Infect Immun. 2002;70:5808-15 pubmed

product information

Product Type :

Antibody

Product Name :

CD14 Monoclonal Antibody (B-A8)

Catalog # :

MA1-19240

Quantity :

100 µg

Price :

US 366

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay Dependent, Flow Cytometry: Assay Dependent, Immunohistochemistry (Paraffin): 2-10 µg/mL

Species :

Human

Clone :

B-A8

Isotype :

IgG1

Storage :

4° C, do not freeze

Description :

CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.

Immunogen :

Human monocytes.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay Dependent, Flow Cytometry: Assay Dependent, Immunohistochemistry (Paraffin): 2-10 µg/mL

Aliases :

CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; Monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; Myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14

more info or order :

Invitrogen product webpage