CD14 Monoclonal Antibody (MEM-15) | Invitrogen MA1-19223 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD14 Monoclonal Antibody (MEM-15)

catalog :

MA1-19223

quantity :

100 µg

price :

US 288

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MEM-15

reactivity :

human

application :

immunoprecipitation, flow cytometry

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 1a	Mewhort H, Lipon B, Svystonyuk D, Teng G, Guzzardi D, Silva C, et al. Monocytes increase human cardiac myofibroblast-mediated extracellular matrix remodeling through TGF-Î²1. Am J Physiol Heart Circ Physiol. 2016;310:H716-24 pubmed publisher
flow cytometry; human; fig 3	Schiff D, Rae J, Martin T, Davis B, Curnutte J. Increased phagocyte Fc gammaRI expression and improved Fc gamma-receptor-mediated phagocytosis after in vivo recombinant human interferon-gamma treatment of normal human subjects. Blood. 1997;90:3187-94 pubmed
	Watson J, Pinggera A, Ho H, Greger I. AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions. Nat Commun. 2021;12:5083 pubmed publisher
	Loaiza S, Ferreira S, Chinn T, Kirby A, Tsolaki E, Dondi C, et al. An engineered, quantifiable in vitro model for analysing the effect of proteostasis-targeting drugs on tissue physical properties. Biomaterials. 2018;183:102-113 pubmed publisher
	Lao Peregrín C, Ballesteros J, Fernández M, Zamora Moratalla A, Saavedra A, Gomez Lazaro M, et al. Caffeine-mediated BDNF release regulates long-term synaptic plasticity through activation of IRS2 signaling. Addict Biol. 2017;22:1706-1718 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD14 Monoclonal Antibody (MEM-15)

Catalog # :

MA1-19223

Quantity :

100 µg

Price :

US 288

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Non-human primate

Applications :

Flow Cytometry: 4 µg/mL, Immunoprecipitation: Assay Dependent

Species :

Human, Non-human primate

Clone :

MEM-15

Isotype :

IgG1

Storage :

4° C, do not freeze

Description :

CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.

Immunogen :

Human urinary proteins from the urine of a patient suffering from proteinuria.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 4 µg/mL, Immunoprecipitation: Assay Dependent

Aliases :

CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; Monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; Myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14

more info or order :

Invitrogen product webpage